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Anti-IFI30 Antibody (4Q235)
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Catalog No. TMAY-02400
Alias IP-30, IP30, interferon γ inducible protein 30, interferon gamma inducible protein 30, IFI-30, IFI30, GILT
Anti-IFI30 Antibody (4Q235) is a Rabbit antibody targeting IFI30. Anti-IFI30 Antibody (4Q235) can be used in IHC-P,ICC/IF.
Anti-IFI30 Antibody (4Q235)
Anti-IFI30 Antibody (4Q235)
😃Good
Catalog No. TMAY-02400Alias IP-30, IP30, interferon γ inducible protein 30, interferon gamma inducible protein 30, IFI-30, IFI30, GILT
Anti-IFI30 Antibody (4Q235) is a Rabbit antibody targeting IFI30. Anti-IFI30 Antibody (4Q235) can be used in IHC-P,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-IFI30 Antibody (4Q235) is a Rabbit antibody targeting IFI30. Anti-IFI30 Antibody (4Q235) can be used in IHC-P,ICC/IF. |
| Alias | IP-30, IP30, interferon γ inducible protein 30, interferon gamma inducible protein 30, IFI-30, IFI30, GILT |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4Q235 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human IFI30 in human tonsil with rabbit monoclonal antibody (1:20000, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human IFI30 in human lung with rabbit monoclonal antibody (1:20000, formalin-fixed paraffin embedded sections). 3. Immunofluorescence staining of IFI30 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti- IFI30 monoclonal antibody (dilution ratio 1:30) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cytoplasm. |
| Application | IHC-P,ICC/IF |
| Recommended Dose | IHC-P: 1:10000-1:20000; ICC-IF: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human IFI30 (rh IFI30; TMPY-02887; P13284; Met1-Lys243). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | IFI30 belongs to the GILT family. This family includes the two characterized human gamma-interferon-inducible lysosomal thiol reductase (GILT) sequences: P13284 and Q9UL08. It also contains several other eukaryotic putative proteins with similarity to GILT. The aligned region contains three conserved cysteine residues. Besides, the two GILT sequences possess a C-X(2)-C motif that is shared by some of the other sequences in the family. This motif is thought to be associated with disulfide bond reduction. IFI30 is a lysosomal thiol reductase that can reduce protein disulfide bonds. It facilitates the generation of MHC class II-restricted epitopes from disulfide bond-containing antigens by the endocytic reduction of disulfide bonds. It also facilitates MHC class I-restricted recognition of exogenous antigens containing disulfide bonds by CD8+ T-cells or cross-presentation. IFI30 may facilitate the complete unfolding of proteins destined for lysosomal degradation and plays an important role in antigen processing. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human IFI30 Protein (TMPY-02887) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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