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(S)-Flurbiprofen

Name: (S)-Flurbiprofen
Brand: TargetMol
SKU: T5843L
Price: 41 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5843LCas No. 51543-39-6

Alias esflurbiprofen

Esflurbiprofen is an inhibitor of COX-1 and COX-2.

(S)-Flurbiprofen

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Purity: 99.99%

Catalog No. T5843LAlias esflurbiprofenCas No. 51543-39-6

Esflurbiprofen is an inhibitor of COX-1 and COX-2.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$29	In Stock	In Stock
50 mg	Preferential	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$41	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:99.99%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Esflurbiprofen is an inhibitor of COX-1 and COX-2.
Targets&IC50	COX-2:0.47 μM, COX-1:0.48 μM
In vitro	(S)-Flurbiprofen (10–7 M) results in a total suppression of basal and stimulated PGE2 release in rat skin.
Synonyms	esflurbiprofen

Chemical Properties

Molecular Weight	244.26
Formula	C₁₅H₁₃FO₂
Cas No.	51543-39-6
Smiles	C[C@H](C(O)=O)c1ccc(c(F)c1)-c1ccccc1
Relative Density.	1.199 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 95 mg/mL (388.93 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0940 mL	20.4700 mL	40.9400 mL	204.6999 mL
5 mM	0.8188 mL	4.0940 mL	8.1880 mL	40.9400 mL
10 mM	0.4094 mL	2.0470 mL	4.0940 mL	20.4700 mL
20 mM	0.2047 mL	1.0235 mL	2.0470 mL	10.2350 mL
50 mM	0.0819 mL	0.4094 mL	0.8188 mL	4.0940 mL
100 mM	0.0409 mL	0.2047 mL	0.4094 mL	2.0470 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc