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Anti-CD31/PECAM-1 Antibody (1E578)
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Catalog No. TMAY-00352
Alias platelet/endothelial cell adhesion molecule 1, PECAM-1, Pecam, Cd31, C85791
Anti-CD31/PECAM-1 Antibody (1E578) is a Rabbit antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (1E578) can be used in ICC/IF.
Anti-CD31/PECAM-1 Antibody (1E578)
Anti-CD31/PECAM-1 Antibody (1E578)
😃Good
Catalog No. TMAY-00352Alias platelet/endothelial cell adhesion molecule 1, PECAM-1, Pecam, Cd31, C85791
Anti-CD31/PECAM-1 Antibody (1E578) is a Rabbit antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (1E578) can be used in ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ICC/IF Reactivity: Human |
| Alias | platelet/endothelial cell adhesion molecule 1, PECAM-1, Pecam, Cd31, C85791 |
| Ig Type | Rabbit IgG |
| Clone | 1E578 |
| Reactivity | Human |
| Verified Activity | Immunofluorescence staining of Human CD31 in HUVEC cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-Human CD31 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody. Positive staining was localized to cell membrane. |
| Application | ICC/IF |
| Recommended Dose | ICC-IF: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD31 / PECAM-1 (rh CD31 / PECAM-1; TMPY-00970; EAW94208.1; Met1-Lys601). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CD31 / PECAM-1 Protein (TMPY-00970) |
| Antigen Species | Human |
| Biology Area | Hemangioblast Markers, ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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