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Anti-CD31/PECAM-1 Antibody (1E578)

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Catalog No. TMAY-00352
Alias platelet/endothelial cell adhesion molecule 1, PECAM-1, Pecam, Cd31, C85791

Anti-CD31/PECAM-1 Antibody (1E578) is a Rabbit antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (1E578) can be used in ICC/IF.

Anti-CD31/PECAM-1 Antibody (1E578)

Anti-CD31/PECAM-1 Antibody (1E578)

😃Good
Catalog No. TMAY-00352Alias platelet/endothelial cell adhesion molecule 1, PECAM-1, Pecam, Cd31, C85791
Anti-CD31/PECAM-1 Antibody (1E578) is a Rabbit antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (1E578) can be used in ICC/IF.
Pack SizePriceAvailabilityQuantity
20 μL$92 7-10 days
100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CD31/PECAM-1 Antibody (1E578) is a Rabbit antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody (1E578) can be used in ICC/IF.
Aliasplatelet/endothelial cell adhesion molecule 1, PECAM-1, Pecam, Cd31, C85791
Ig Type
Monoclonal Rabbit IgG
Clone
1E578
Reactivity
Human
Verified Activity
Immunofluorescence staining of Human CD31 in HUVEC cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with rabbit anti-Human CD31 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody. Positive staining was localized to cell membrane.
Application
ICC/IF
Recommended Dose
ICC-IF: 1:20-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CD31 / PECAM-1 (rh CD31 / PECAM-1; TMPY-00970; EAW94208.1; Met1-Lys601).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human CD31 / PECAM-1 Protein (TMPY-00970)
Antigen Species
Human
Biology Area
Hemangioblast Markers, ITIM/ITAM Immunoreceptors and Related Molecules
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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