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Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody
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Catalog No. TMAC-00118
Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AKT1 (Ser246). Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA.
Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody
Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody
😃Good
Catalog No. TMAC-00118
Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AKT1 (Ser246). Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $316 | 7-10 days |
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| Description | Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AKT1 (Ser246). Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:5000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Appearance | Liquid |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research Background | AKT serine/threonine kinase 1(AKT1) Homo sapiens The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011] |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human Akt around the phosphorylation site of Ser246. AA range:212-261 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 56 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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