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Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody

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Catalog No. TMAC-00118

Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AKT1 (Ser246). Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA.

Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody

Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody

😃Good
Catalog No. TMAC-00118
Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AKT1 (Ser246). Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2187-10 days
100 μL$3167-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AKT1 (Ser246). Anti-Phospho-AKT1 (Ser246) Polyclonal Antibody can be used in WB,IHC-P,ICC/IF,ELISA.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:5000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research BackgroundAKT serine/threonine kinase 1(AKT1) Homo sapiens The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human Akt around the phosphorylation site of Ser246. AA range:212-261
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 56 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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