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NDRG1 Protein, Human, Recombinant (His)
(Synonyms: TDD5, TARG1, RTP, RIT42, PROXY1, N-myc downstream regulated 1, NMSL, NDR1, HMSNL, GC4, DRG-1, DRG1, CMT4D, CAP43) Copy Product InfoSynonyms: TDD5, TARG1, RTP, RIT42, PROXY1, N-myc downstream regulated 1, NMSL, NDR1, HMSNL, GC4, DRG-1, DRG1, CMT4D, CAP43
Catalog No. TMPY-03443 Copy Product Info
NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Mutations in the NDRG1 gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. NDRG1 is a stress-responsive protein involved in hormone responses, cell growth, and differentiation. It acts as a tumor suppressor in many cell types.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $48 | - | In Stock | |
| 10 μg | $76 | - | In Stock | |
| 20 μg | $118 | 7-10 days | 7-10 days | |
| 50 μg | $237 | 7-10 days | 7-10 days | |
| 100 μg | $458 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 85 % as determined by SDS-PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Mutations in the NDRG1 gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. NDRG1 is a stress-responsive protein involved in hormone responses, cell growth, and differentiation. It acts as a tumor suppressor in many cell types. |
| Species | Human |
| Expression System | E. coli |
| Tag | C-His |
| Accession Number | Q92597 |
| Construction | A DNA sequence encoding the human NDRG1 (Q92597) (Met1-Cys394) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Met |
| Protein Purity | > 85 % as determined by SDS-PAGE |
| Endotoxin | Please contact us for more information. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | TDD5, TARG1, RTP, RIT42, PROXY1, N-myc downstream regulated 1, NMSL, NDR1, HMSNL, GC4, DRG-1, DRG1, CMT4D, CAP43 |
| Research Background |
| Molecular Weight | 43.8 kDa (predicted); 43 kDa (reducing conditions) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: NDRG1 Protein, Human, Recombinant (His) chemical structure | NDRG1 Protein, Human, Recombinant (His) molecular weight
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