IL-10 Protein, Human, Recombinant (CHO)

Name: IL-10 Protein, Human, Recombinant (CHO)
Brand: TargetMol
SKU: TMPS-00057
Rating: 4.5 (1 reviews)

(Synonyms: TGIF, CSIF, B-TCGF) Copy Product Info

Synonyms: TGIF, CSIF, B-TCGF

Catalog No. TMPS-00057 Copy Product Info

IL-10 Protein, Human, Recombinant (CHO) is expressed in CHO Cells. The accession number is P22301.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$98	7-10 days	7-10 days
10 µg	$170	7-10 days	7-10 days
20 µg	$295	7-10 days	7-10 days
50 µg	$622	7-10 days	7-10 days
100 µg	$993	7-10 days	7-10 days
200 µg	$1,580	7-10 days	7-10 days
500 µg	$2,960	7-10 days	7-10 days
1 mg	$4,750	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	ED 50 < 2.0 ng/ml, measured in a cell proliferation assay using MC/9 cells.
Description	IL-10 Protein, Human, Recombinant (CHO) is expressed in CHO Cells. The accession number is P22301.
Species	Human
Expression System	CHO Cells
Tag	Tag Free
Accession Number	P22301
Construction	Ser19-Asn178
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	TGIF, CSIF, B-TCGF
Research Background	Interleukin-10 (IL-10), initially known as Cytokine Synthesis Inhibitory Factor (CSIF), belongs to the IL-10 family and shares more than 80% sequence homology with Epstein-Barr Virus protein BCRFI. It is produced by many immune cells, such as T-cells, macrophages, mast cells, and dendritic cells. It is usually secreted as a homodimer and, upon binding to its receptor, inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and Th2 cells. It also displays ability to suppress Antigen-Presenting Cell (APC) function. The net effect of Interleukin-10 appears to be inhibitory; however, stimulatory effects, such as stimulation of B cell maturation and antibody production, are also reported.

Chemical Properties

Molecular Weight

18~19 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.