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Toll-like receptor modulator

Name: Toll-like receptor modulator
Brand: TargetMol
SKU: T13182
Rating: 4.5 (1 reviews)

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Catalog No. T13182Cas No. 926927-42-6

Toll-like receptor modulator is a TLR7/8 modulator that regulates immune function.

Toll-like receptor modulator

😃Good

Catalog No. T13182Cas No. 926927-42-6

Toll-like receptor modulator is a TLR7/8 modulator that regulates immune function.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
2 mg	$65	5 days	5 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Toll-like receptor modulator is a TLR7/8 modulator that regulates immune function.
In vitro	Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.

Chemical Properties

Molecular Weight	348.27
Formula	C₁₅H₁₃F₅N₂O₂
Cas No.	926927-42-6
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (287.13 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8713 mL	14.3567 mL	28.7134 mL	143.5668 mL
5 mM	0.5743 mL	2.8713 mL	5.7427 mL	28.7134 mL
10 mM	0.2871 mL	1.4357 mL	2.8713 mL	14.3567 mL
20 mM	0.1436 mL	0.7178 mL	1.4357 mL	7.1783 mL
50 mM	0.0574 mL	0.2871 mL	0.5743 mL	2.8713 mL
100 mM	0.0287 mL	0.1436 mL	0.2871 mL	1.4357 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc