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1-Pyrenebutyric acid NHS ester
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Catalog No. T66661Cas No. 114932-60-4
Alias 1-Pyrenebutyric acid N-hydroxysuccinimide ester
1-Pyrenebutyric acid NHS ester is an aromatic reagent widely used for biomolecule labeling. the NHS ester of 1-Pyrenebutyric acid NHS ester functionality enables covalent conjugation to amine-containing substrates, supporting applications in nucleic acid detection, protein immobilization, and characterization of cyclodextrin-based polyrotaxanes. Its pyrene fluorophore makes it suitable for fluorescence-based analytical studies.
1-Pyrenebutyric acid NHS ester
😃Good
Purity: 99.62%
Catalog No. T66661Alias 1-Pyrenebutyric acid N-hydroxysuccinimide esterCas No. 114932-60-4
1-Pyrenebutyric acid NHS ester is an aromatic reagent widely used for biomolecule labeling. the NHS ester of 1-Pyrenebutyric acid NHS ester functionality enables covalent conjugation to amine-containing substrates, supporting applications in nucleic acid detection, protein immobilization, and characterization of cyclodextrin-based polyrotaxanes. Its pyrene fluorophore makes it suitable for fluorescence-based analytical studies.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 2 mg | $30 | - | In Stock | |
| 5 mg | $38 | - | In Stock | |
| 10 mg | $52 | - | In Stock | |
| 25 mg | $84 | - | In Stock | |
| 50 mg | $119 | - | In Stock | |
| 100 mg | $173 | - | In Stock | |
| 500 mg | $432 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.62%
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Product Introduction
Bioactivity
Chemical Properties
| Description | 1-Pyrenebutyric acid NHS ester is an aromatic reagent widely used for biomolecule labeling. the NHS ester of 1-Pyrenebutyric acid NHS ester functionality enables covalent conjugation to amine-containing substrates, supporting applications in nucleic acid detection, protein immobilization, and characterization of cyclodextrin-based polyrotaxanes. Its pyrene fluorophore makes it suitable for fluorescence-based analytical studies. |
| In vitro | In in vitro experiments, antibodies were immobilized on the surface of CNT-FET circuits via a 1-hour reaction with 1-Pyrenebutyric acid NHS ester at a concentration of 5 mM [3]. 1-Pyrenebutyric acid NHS ester was employed as an interfacial coupling reagent, which enabled the efficient immobilization of SARS-CoV-2 spike antibodies on the surface of graphene sheets. This immobilization strategy provided critical support for the construction of field-effect transistor (FET)-based biosensors, which can be used for the specific detection of SARS-CoV-2 [5]. |
| Synonyms | 1-Pyrenebutyric acid N-hydroxysuccinimide ester |
| Molecular Weight | 385.42 |
| Formula | C24H19NO4 |
| Cas No. | 114932-60-4 |
| Smiles | O=C(ON1C(=O)CCC1=O)CCCC2=CC=C3C=CC4=CC=CC=5C=CC2=C3C45 |
| Color | Yellow |
| Appearance | Solid |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility Information | DMSO: ≥ 80 mg/mL, Sonication is recommended. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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