Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Thalidomide-NH-PEG3-COOH is a conjugate of the E3 ligase ligand-linker synthesized compound, which integrates a cereblon ligand based on Thalidomide and a linker employed in PROTAC technology.
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Description | Thalidomide-NH-PEG3-COOH is a conjugate of the E3 ligase ligand-linker synthesized compound, which integrates a cereblon ligand based on Thalidomide and a linker employed in PROTAC technology. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Synonyms | Thalidomide-NH-PEG3-COOH |
Molecular Weight | 477.47 |
Formula | C22H27N3O9 |
CAS No. | 2375283-62-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Thalidomide-NH-PEG3-COOH 2375283-62-6 Thalidomide NH PEG3 COOH ThalidomideNHPEG3COOH Thalidomide-NH-PEG-3-COOH inhibitor inhibit