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C18 Phytoceramide (t18:0/18:0)

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Catalog No. T37458Cas No. 34354-88-6
Alias N-Stearoyl phytosphingosine, Ceramide 3

C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid present in Saccharomyces cerevisiae, wheat grains, and the mammalian epidermal stratum corneum, composed of a phytosphingosine backbone amide-linked to a C18 fatty acid chain, C18 Phytoceramide regulates apoptosis, cell differentiation, smooth muscle cell proliferation, and mitochondrial respiratory chain activity while inhibiting IL-4, TNF-α, c-Jun, and NF-κB expression in histone-stimulated murine skin tissue, supporting its use in dermatological, inflammatory, and cosmetic skin barrier research.

C18 Phytoceramide (t18:0/18:0)

C18 Phytoceramide (t18:0/18:0)

😃Good
Catalog No. T37458Alias N-Stearoyl phytosphingosine, Ceramide 3Cas No. 34354-88-6
C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid present in Saccharomyces cerevisiae, wheat grains, and the mammalian epidermal stratum corneum, composed of a phytosphingosine backbone amide-linked to a C18 fatty acid chain, C18 Phytoceramide regulates apoptosis, cell differentiation, smooth muscle cell proliferation, and mitochondrial respiratory chain activity while inhibiting IL-4, TNF-α, c-Jun, and NF-κB expression in histone-stimulated murine skin tissue, supporting its use in dermatological, inflammatory, and cosmetic skin barrier research.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$69835 days35 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
C18 Phytoceramide (t18:0/18:0) (Cer(t18:0/18:0)) is a bioactive sphingolipid present in Saccharomyces cerevisiae, wheat grains, and the mammalian epidermal stratum corneum, composed of a phytosphingosine backbone amide-linked to a C18 fatty acid chain, C18 Phytoceramide regulates apoptosis, cell differentiation, smooth muscle cell proliferation, and mitochondrial respiratory chain activity while inhibiting IL-4, TNF-α, c-Jun, and NF-κB expression in histone-stimulated murine skin tissue, supporting its use in dermatological, inflammatory, and cosmetic skin barrier research.
SynonymsN-Stearoyl phytosphingosine, Ceramide 3
Chemical Properties
Molecular Weight583.98
FormulaC36H73NO4
Cas No.34354-88-6
Smiles[C@H]([C@@H]([C@@H](CCCCCCCCCCCCCC)O)O)(NC(CCCCCCCCCCCCCCCCC)=O)CO
Relative Density.0.994-1.014 g/cm3 at 20℃
Storage & Solubility Information
StorageIn solvent: -80°C for 1 year
Solubility Information
Chloroform:Methanol (1:1): Soluble, Heating is recommended.
Methanol: 0.8 mg/mL (1.37 mM), Sonication is recommended.
Solution Preparation Table
Methanol
1mg5mg10mg50mg
1 mM1.7124 mL8.5619 mL17.1239 mL85.6194 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

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