keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate (2'-ANT-GTP) and 3'-ANT-GTP are fluorescent derivatives of GTP that exhibit spontaneous isomerization. 2'(3')-ANT-GTP features an emission peak at 428 nm when excited at 330 nm in aqueous conditions. It functions as an inhibitor of several adenylyl cyclases, notably mammalian adenylyl cyclase 1 (AC1; Ki = 10 nM with manganese), inhibits B. anthracis adenylyl cyclase toxin edema factor (Kis = 4.1 and 13 µM with manganese and magnesium, respectively), and B. pertussis adenylyl cyclase toxin CyaA (Ki = 29 µM with manganese).
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Description | 2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate (2'-ANT-GTP) and 3'-ANT-GTP are fluorescent derivatives of GTP that exhibit spontaneous isomerization. 2'(3')-ANT-GTP features an emission peak at 428 nm when excited at 330 nm in aqueous conditions. It functions as an inhibitor of several adenylyl cyclases, notably mammalian adenylyl cyclase 1 (AC1; Ki = 10 nM with manganese), inhibits B. anthracis adenylyl cyclase toxin edema factor (Kis = 4.1 and 13 µM with manganese and magnesium, respectively), and B. pertussis adenylyl cyclase toxin CyaA (Ki = 29 µM with manganese). |
Synonyms | 2'(3')-ANT-GTP |
Molecular Weight | 730.23 |
Formula | C17H17N6O15P3.4Na |
keep away from direct sunlight
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: Soluble
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2'(3')-O-Anthraniloylguanosine-5'-O-triphosphate sodium 2'(3')-ANT-GTP inhibitor inhibit