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Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 2
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Catalog No. TMAC-03759
Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SIRT1 (Ser47). Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody can be used in WB.
Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 2
Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 2
😃Good
Catalog No. TMAC-03759
Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SIRT1 (Ser47). Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $217 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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Chemical Properties
| Description | Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SIRT1 (Ser47). Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 47(E-R-S(p)-P-G) derived from Human SirT1 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 110 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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