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Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 2

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Catalog No. TMAC-03759

Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SIRT1 (Ser47). Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody can be used in WB.

Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 2

Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody 2

😃Good
Catalog No. TMAC-03759
Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SIRT1 (Ser47). Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2177-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SIRT1 (Ser47). Anti-Phospho-SIRT1 (Ser47) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundNAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 47(E-R-S(p)-P-G) derived from Human SirT1
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 110 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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