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TargetMol | Compound Library

Anti-Ovarian Cancer Compound Library

Catalog No. L2196

Ovarian cancer is a malignant tumor that develops in the ovarian tissue. Approximately 90% to 95% of ovarian cancers are primary, meaning they form within the ovaries, while the remaining 5% to 10% are metastatic cancers that have spread to the ovaries from other sites. Early-stage ovarian cancer typically presents with no distinct symptoms, and even when symptoms are present, they lack specificity, making early diagnosis relatively challenging. About 60% to 70% of patients are diagnosed at an advanced stage with poor treatment outcomes. Although the occurrence of ovarian cancer is lower than that of cervical and endometrial cancers, its mortality rate is much higher. Ovarian cancer ranks as the leading cause of mortality among malignant tumors of the female reproductive tract, and mortality rate has been on the rise, posing a significant threat to women's health. Effectively improving the survival period of ovarian cancer patients has become a pressing challenge.
In recent years, there has been remarkable progress in the development of molecular targeted therapies. It's shown that targeted drugs for the ovarian cancer play a significant role in enhancing patient survival. The development of targeted therapies has brought hope to ovarian cancer patients, offering them more effective treatment strategies.
The TargetMol anti-ovarian cancer compound library comprises a collection of Xnum compounds, including compounds reported to exhibit therapeutic effects against ovarian cancer as well as compounds with the potential for treating ovarian cancer. The library serves as a valuable tool for the research and development of anti-ovarian cancer drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2196

Anti-Ovarian Cancer Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 2232 compounds with anti-ovarian cancer therapeutic activity, can be used for anti-ovarian cancer drug discovery and pharmacological study;
  • Targets include PARP, VEGF, PD-1, HER2, etc;
  • Some compounds have already been launched or are in clinical phases.
  • Detailed compound information on structures, targets, IC50 and activity descriptions.
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
NF-κB
Autophagy
PI3K
EGFR
Reactive Oxygen Species
ROS
Ras
VEGFR
p38 MAPK
Wnt/beta-catenin
ERK
Akt
mTOR
Endogenous Metabolite
PARP
Estrogen Receptor/ERR
Antibacterial
GSK-3
AMPK
Raf
TGF-beta/Smad
CDK
JNK
PDGFR
MAPK
Estrogen/progestogen Receptor
TNF
COX
IκB/IKK
Caspase
MEK
FGFR
Src
Kras
Parasite
FLT
c-Kit
RIP kinase
NO Synthase
DNA-PK
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S6 Kinase
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STAT
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ATM/ATR
PPAR
HER
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ALK
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Casein Kinase
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Aurora Kinase
IGF-1R
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BTK
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HIF/HIF Prolyl-Hydroxylase
Phosphatase
TLR
Microtubule Associated
FAK
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p53
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c-Fms
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P-gp
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NOS
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CSF-1R
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DNA Alkylation
Immunology/Inflammation related
DUB
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S1P Receptor
BACE
NADPH
Glucocorticoid Receptor
Lipid
Monoamine Oxidase
Y Box Binding Protein 1
Liver X Receptor
PAK
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Fatty Acid Synthase
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glycosidase
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gp120/CD4
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AAK1
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Adenosine Deaminase
Apelin receptor
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CD38
VDA
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Monoamine Transporter
FAAH
DNA
CD74
cGAS
CRISPR/Cas9
Hydroxylase
YAP
OCT
Hck
Stemness kinase
IDO
Phosphorylase
Na-K-Cl cotransporter
SGLT

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