Anti-Ovarian Cancer Compound Library

Catalog No. L2196

Library Compound List Excel SDF

Ovarian cancer is a malignant tumor that develops in the ovarian tissue. Approximately 90% to 95% of ovarian cancers are primary, meaning they form within the ovaries, while the remaining 5% to 10% are metastatic cancers that have spread to the ovaries from other sites. Early-stage ovarian cancer typically presents with no distinct symptoms, and even when symptoms are present, they lack specificity, making early diagnosis relatively challenging. About 60% to 70% of patients are diagnosed at an advanced stage with poor treatment outcomes. Although the occurrence of ovarian cancer is lower than that of cervical and endometrial cancers, its mortality rate is much higher. Ovarian cancer ranks as the leading cause of mortality among malignant tumors of the female reproductive tract, and mortality rate has been on the rise, posing a significant threat to women's health. Effectively improving the survival period of ovarian cancer patients has become a pressing challenge.

In recent years, there has been remarkable progress in the development of molecular targeted therapies. It’s shown that targeted drugs for the ovarian cancer play a significant role in enhancing patient survival. The development of targeted therapies has brought hope to ovarian cancer patients, offering them more effective treatment strategies.

The TargetMol anti-ovarian cancer compound library comprises a collection of Xnum compounds, including compounds reported to exhibit therapeutic effects against ovarian cancer as well as compounds with the potential for treating ovarian cancer. The library serves as a valuable tool for the research and development of anti-ovarian cancer drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)

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If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com

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Product Description

A unique collection of 1888 compounds with anti-ovarian cancer therapeutic activity, can be used for anti-ovarian cancer drug discovery and pharmacological study;
Targets include PARP, VEGF, PD-1, HER2, etc;
Some compounds have already been launched or are in clinical phases.
Detailed compound information on structures, targets, IC50 and activity descriptions.
NMR and HPLC/LCMS validated to ensure high purity and quality.

Library Customization

Targetmol Compound Libraries can be highly customized! Learn More

Packaging And Storage

Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
Shipped with blue ice

Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (13.2 MB) Request for Library Compostion in Excel and SDF files

Publications Cited TargetMol Libraries

1. Cell Stem Cell. 2022 Apr 29(4) 545–558. 2. Science Bulletin. 2022. 3. Science Translational Medicine. 2022, 14(656): eabn3231. 4. Science Advances. 2023, 9(9): eade3760. 5. Nature. 2020, 582: 289-293. 6. Nature Biotechnology. 2021, 39(11): 1444-1452. 7. Nature Communications. 2022, 13(1): 1-15.. 8. Nature Communications. 2023, 14(1): 1020.. 9. Nature Communications. 2023, 14(1): 2756..

10. Blood. 2021, 137(11): 1478-1490. 11. Nucleic Acids Research. 2021. 12. Nature Communications. 2023, 14(1): 7574. 13. Advanced Science. 2020, 7(16): 2000925. 14. Angewandte Chemie. 2021. 15. Acta Pharmaceutica Sinica B. 2022. 16. Protein & Cell. 2021, 12(11): 877-888. 17. Bone Research. 2023, 11(1): 54. 18. Pharmacology & Therapeutics. (2021): 107930. 19. Nature Communications. 2021, 12(1): 1-12. 20. Journal of Cell Biology. 2022, 221(5): e202112024.

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Library Composition

Apoptosis (323)

Autophagy (252)

NF-κB (227)

PI3K (180)

EGFR (164)

Reactive Oxygen Species (160)

VEGFR (149)

mTOR (97)

Akt (96)

ERK (92)

p38 MAPK (91)

Endogenous Metabolite (91)

Wnt/beta-catenin (88)

Estrogen Receptor/ERR (81)

AMPK (81)

PARP (73)

Raf (70)

Antibacterial (68)

PDGFR (61)

Ras (60)

GSK-3 (59)

CDK (58)

Estrogen/progestogen Receptor (52)

TGF-beta/Smad (51)

JNK (48)

MAPK (46)

MEK (45)

Src (42)

FGFR (42)

COX (41)

FLT (40)

c-Kit (40)

IκB/IKK (40)

DNA-PK (37)

TNF (33)

S6 Kinase (31)

Caspase (30)

Parasite (27)

STAT (25)

Ferroptosis (25)

HER (25)

RIP kinase (25)

Antifungal (24)

Influenza Virus (23)

ATM/ATR (23)

PKC (22)

c-Met/HGFR (22)

ALK (22)

NOD (21)

IL Receptor (21)

Antibiotic (20)

P450 (19)

Antioxidant (19)

Mitophagy (19)

PDK (19)

Bcr-Abl (19)

HIV Protease (19)

DNA/RNA Synthesis (18)

Aurora Kinase (18)

PPAR (17)

JAK (17)

IRAK (17)

c-RET (17)

Calcium Channel (16)

NO Synthase (16)

Topoisomerase (15)

IGF-1R (14)

PKA (14)

Potassium Channel (14)

Casein Kinase (14)

ROS (13)

PI4K (13)

NOD-like Receptor (NLR) (13)

MMP (13)

PD-1/PD-L1 (13)

Rho (13)

Nrf2 (12)

BCL (12)

p53 (11)

Lipoxygenase (11)

Interleukin (10)

Mitochondrial Metabolism (10)

c-Fms (10)

Chk (10)

Tyrosine Kinases (10)

Tyrosinase (9)

HDAC (9)

TLR (8)

PTEN (8)

Beta Amyloid (8)

Dehydrogenase (8)

HIF/HIF Prolyl-Hydroxylase (8)

MLK (8)

FAK (8)

ROCK (8)

MNK (7)

E1/E2/E3 Enzyme (7)

Virus Protease (7)

Trk receptor (7)

Drug Metabolite (7)

Sodium Channel (7)

GABA Receptor (7)

Microtubule Associated (7)

TAM Receptor (6)

NOS (6)

SIK (6)

PDE (6)

HSV (6)

HCV Protease (6)

Prostaglandin Receptor (6)

AChR (6)

Syk (6)

MELK (5)

AChE (5)

HSP (5)

DNA Alkylation (5)

HIF (5)

BTK (5)

Adrenergic Receptor (5)

transporter (5)

Transferase (5)

Antiviral (5)

TOPK (5)

ASK (5)

Tie-2 (5)

SGK (5)

Ephrin Receptor (5)

Proteasome (5)

Epigenetic Reader Domain (5)

P-gp (5)

Serine Protease (4)

NADPH (4)

S1P Receptor (4)

Porcupine (4)

PLK (4)

Phosphatase (4)

LDL (4)

5-HT Receptor (4)

Integrin (4)

CaMK (4)

IAP (4)

Free radical scavengers (4)

ATPase (4)

Carbonic Anhydrase (4)

Aryl Hydrocarbon Receptor (4)

Anti-infection (4)

Opioid Receptor (3)

Cannabinoid Receptor (3)

PGE Synthase (3)

GTPase (3)

BACE (3)

RAAS (3)

HBV (3)

c-Myc (3)

Reductase (3)

Aromatase (3)

LRRK2 (3)

Sirtuin (3)

Glutathione Peroxidase (3)

Histamine Receptor (3)

Antifection (3)

Androgen Receptor (3)

Glucosidase (3)

KLF (3)

Proton pump (3)

DNA Alkylator/Crosslinker (3)

Chloride channel (3)

Reverse Transcriptase (3)

MAO (3)

Adenosine Receptor (3)

CSF-1R (3)

Glucocorticoid Receptor (2)

PAI-1 (2)

cAMP (2)

Retinoid Receptor (2)

SARS-CoV (2)

DYRK (2)

DUB (2)

Pim (2)

Dopamine Receptor (2)

CCR (2)

RANKL/RANK (2)

GluR (2)

NADPH-oxidase (2)

IRE1 (2)

Leukotriene Receptor (2)

ACK (2)

Liver X Receptor (2)

Mdm2 (2)

IFNAR (2)

AhR (2)

MRP (2)

TRP/TRPV Channel (2)

GST (2)

BMI-1 (2)

Beta-Secretase (2)

STING (2)

cGAS (1)

CRISPR/Cas9 (1)

Smo (1)

Wee1 (1)

Adenosine deaminase (1)

VDA (1)

cholecystokinin (1)

Stemness kinase (1)

SGLT (1)

ROR (1)

ATP Citrate Lyase (1)

CFTR (1)

RSV (1)

Aminopeptidase (1)

Somatostatin (1)

Apelin receptor (1)

BCRP (1)

cell cycle arrest (1)

Arginase (1)

Serine/threonin kinase (1)

Kinesin (1)

DNA Methyltransferase (1)

RAR/RXR (1)

Hippo pathway (1)

NPC1L1 (1)

GPX (1)

Haspin Kinase (1)

NMDAR (1)

NEDD8 (1)

Hck (1)

Myosin (1)

Hedgehog/Smoothened (1)

Monoamine Oxidase (1)

Histone Acetyltransferase (1)

Nucleoside Antimetabolite/Analog (1)

Histone Demethylase (1)

Histone Methyltransferase (1)

Hydroxylase (1)

Methionine Adenosyltransferase (MAT) (1)

Immunology/Inflammation related (1)

LTR (1)

LPL Receptor (1)

Indoleamine 2,3-Dioxygenase (IDO) (1)

Ligand for E3 Ligase (1)

GPR (1)

OCT (1)

PYK2 (1)

Phosphorylase (1)

CXCR (1)

Cysteine Protease (1)

DAPK (1)

Progesterone Receptor (1)

DHFR (1)

Discoidin Domain Receptor (DDR) (1)

DNA (1)

Platelet aggregation (1)

PKM (1)

Phospholipase (1)

Glutathione reductase (1)

FAAH (1)

Fatty Acid Synthase (1)

PERK (1)

FXR (1)

Gamma-secretase (1)

Gap Junction Protein (1)

Glucokinase (1)

PAK (1)

OXPHOS (1)

YAP (1)

Library Information Sample

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty