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TargetMol | Compound Library

Calcium Channel Compound Library

Catalog No. L7200

A calcium channel is an ion channel(plasma membrane protein) which shows selective permeability to calcium ions. Calcium channels constitute a large family of voltage- and ligand-operated ion channels. Calcium channels are ubiquitous, they can be found in almost any type of excitable (e.g., muscle, glial cells, neurons, etc.) and most unexcitable cells in a wide variety of species. Functions mediated by calcium channels include contraction of muscle, release of neurotransmitters and hormones by neurons and neuroendocrine cells, and control of gene transcription. They are targets for modulation by many intracellular signaling pathways including G proteins and phosphorylation. Calcium channels play pivotal roles in many human diseases, particularly of the cardiac and nervous systems, including pain, seizure, hypertension and migraine. Pharmacological blockers for some types of calcium channels are known, including clinically used drugs for hypertension and pain. In some cases such calcium channel blockers are highly selective for specific types of calcium channels, but there is great potential for developing more selective and more potent drugs targeting calcium channels. TargetMol’s Calcium Channel Library collects the reported calcium channel blockers and agonists, and is an ideal tool for screening more selective and potent drugs targeting calcium channels.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L7200

Calcium Channel Compound Library
sizeIn stock
  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;
  • Targeting different subtypes of calcium channels, such as L-type, T-type, N-type, and receptor-operated calcium channels.
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials, some of which are FDA approved;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Calcium Channel
Autophagy
Sodium Channel
Potassium Channel
Endogenous Metabolite
AChR
Apoptosis
Adrenergic Receptor
NF-κB
TRP/TRPV Channel
Parasite
Reactive Oxygen Species
GABA Receptor
Histamine Receptor
Dopamine Receptor
PKC
COX
P450
HIV Protease
Carbonic Anhydrase
PKA
iGluR
CaMK
P-gp
AMPK
Chloride channel
Src
Reductase
RAAS
Phosphatase
GSK-3
ATPase
p38 MAPK
Antioxidant
Na+/Ca2+ Exchanger
Virus Protease
Wnt/beta-catenin
Serine/threonin kinase
ROCK
Glucocorticoid Receptor
PDE
LDL
PPAR
ERK
PAFR
CDK
Drug Metabolite
P2X Receptor
Monoamine Transporter
ROS
Opioid Receptor
IL Receptor
cAMP
GluR
Interleukin
TGF-beta/Smad
EGFR
DNA/RNA Synthesis
SARS-CoV
Antibacterial
Prostaglandin Receptor
Influenza Virus
GST
5-HT Receptor
Antibiotic
AhR
Anti-infection
DNA Methyltransferase

Keywords