Shopping Cart
- Remove All
- Your shopping cart is currently empty
Amino-PEG4-alcohol is a PEG-based PROTAC linker used for synthesizing PROTACs[1] and a non-cleavable 4-unit PEG ADC linker for synthesizing antibody-drug conjugates (ADCs)[2].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Amino-PEG4-alcohol is a PEG-based PROTAC linker used for synthesizing PROTACs[1] and a non-cleavable 4-unit PEG ADC linker for synthesizing antibody-drug conjugates (ADCs)[2]. |
In vitro | PROTACs, or proteolysis-targeting chimeras, are composed of two distinct ligands joined by a linker. One of these ligands binds to a specific protein target, while the other binds to an E3 ubiquitin ligase. When the PROTAC binds to both the target protein and the E3 ligase, it triggers the ubiquitin-proteasome system within cells to degrade the target protein, thereby providing a mechanism for targeted protein degradation. |
Molecular Weight | 193.24 |
Formula | C8H19NO4 |
Cas No. | 86770-74-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.