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Anti-I-309/CCL1 Antibody (1S849)
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Catalog No. TMAY-00196
Alias TCA3, SISe, SCYA1, P500, I-309, chemokine (C-C motif) ligand 1
Anti-I-309/CCL1 Antibody (1S849) is a Mouse antibody targeting I-309/CCL1. Anti-I-309/CCL1 Antibody (1S849) can be used in ELISA.
Anti-I-309/CCL1 Antibody (1S849)
Anti-I-309/CCL1 Antibody (1S849)
😃Good
Catalog No. TMAY-00196Alias TCA3, SISe, SCYA1, P500, I-309, chemokine (C-C motif) ligand 1
Anti-I-309/CCL1 Antibody (1S849) is a Mouse antibody targeting I-309/CCL1. Anti-I-309/CCL1 Antibody (1S849) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | TCA3, SISe, SCYA1, P500, I-309, chemokine (C-C motif) ligand 1 |
| Ig Type | Mouse IgG2a |
| Clone | 1S849 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human I-309/CCL1 (rh I-309/CCL1; TMPY-00695; NP_002972.1; Lys24-Lys96). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CCL1 or chemokine (C-C motif) ligand 1, also known as I-309 or TCA-3, is a member of the chemokine (C-C motif) ligand family. The C-C chemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. I-309/CCL1/TCA-3 interacts with the G protein-linked transmembrane chemokine receptors CCR8 and induces biochemical events that may result in the control of chemotaxis, proliferation, apoptosis and adhesion. It has been demonstrated that I-309/CCL1/TCA-3 displays chemotactic activity for monocytes and other cell types such as NK cells and dendritic cells, but not for neutrophils. Furthermore, as the only known physiological ligand for CCR8, I-309/CCL1/TCA-3 was identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection. I-309/CCL1/TCA-3 induces significant levels of LTC4 from elicited eosinophils. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human I-309/CCL1 Protein (TMPY-00695) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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