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Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody
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Catalog No. TMAC-01433
Alias PTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PTK2 (Tyr397)
Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTK2 (Tyr397). Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody can be used in IHC,WB.
Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody
Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody
😃Good
Catalog No. TMAC-01433Alias PTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PTK2 (Tyr397)
Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTK2 (Tyr397). Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody can be used in IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $218 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTK2 (Tyr397). Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody can be used in IHC,WB. |
| Synonyms | PTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PTK2 (Tyr397) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extract from 293 cells untreated or treated with EGF using FAK (Phospho-Tyr397) Antibody using TMAC-01433. 2. Immunohistochemical analysis of paraffin-embedded Mouse-brain tissue.   |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 397(D-D-Y(p)-A-E)derived from Human FAK |
| Antigen Species | human |
| Uniprot ID |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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