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Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody (Synonyms: PTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PT...)

Catalog No. TMAC-01433 Copy Product Info
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Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTK2 (Tyr397). Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAC-01433
Synonyms PTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PTK2 (Tyr397)

Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTK2 (Tyr397). Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody can be used in IHC,WB.

Anti-Phospho-PTK2
(Tyr397) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2187-10 days7-10 days
100 μL$3177-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTK2 (Tyr397). Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody can be used in IHC,WB.
SynonymsPTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PTK2 (Tyr397)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of extract from 293 cells untreated or treated with EGF using FAK (Phospho-Tyr397) Antibody using TMAC-01433.
2. Immunohistochemical analysis of paraffin-embedded Mouse-brain tissue.
verifiedActivityverifiedActivity
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundNon-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 397(D-D-Y(p)-A-E)derived from Human FAK
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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