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Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody

(Synonyms: PTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PTK2 (Tyr397)) Copy Product Info
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Synonyms: PTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PTK2 (Tyr397)

Catalog No. TMAC-01433 Copy Product Info
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Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTK2 (Tyr397). Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody can be used in IHC,WB.
Anti-Phospho-PTK2
(Tyr397) Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2187-10 days7-10 days
100 μL$3177-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PTK2 (Tyr397). Anti-Phospho-PTK2 (Tyr397) Polyclonal Antibody can be used in IHC,WB.
SynonymsPTK2 (p-Y397), PTK2 (p-Tyr397), p-PTK2 (Y397), p-PTK2 (Tyr397)
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundNon-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 397(D-D-Y(p)-A-E)derived from Human FAK
Antigen Species
Human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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