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Anti-LYPLA2 Antibody (2Z810)

😃Good
Catalog No. TMAY-02325
Alias lysophospholipase II, DJ886K2.4, APT-2, APT2

Anti-LYPLA2 Antibody (2Z810) is a Mouse antibody targeting LYPLA2. Anti-LYPLA2 Antibody (2Z810) can be used in ELISA.

Anti-LYPLA2 Antibody (2Z810)

Anti-LYPLA2 Antibody (2Z810)

😃Good
Catalog No. TMAY-02325Alias lysophospholipase II, DJ886K2.4, APT-2, APT2
Anti-LYPLA2 Antibody (2Z810) is a Mouse antibody targeting LYPLA2. Anti-LYPLA2 Antibody (2Z810) can be used in ELISA.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-LYPLA2 Antibody (2Z810) is a Mouse antibody targeting LYPLA2. Anti-LYPLA2 Antibody (2Z810) can be used in ELISA.
Aliaslysophospholipase II, DJ886K2.4, APT-2, APT2
Ig Type
Monoclonal Mouse IgG2b
Clone
2Z810
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LYPLA2 (rh LYPLA2; TMPY-02132; O95372; Met 1-Val 231). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundLysophospholipase II (LYPLA2, LPL-II, or LysoPLA II), also known as Acyl-protein thioesterase 2 (APT-2), belongs to the AB hydrolase 2 family. This enzyme has lysophospholipase activity and may hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Acyl-protein thioesterase 1 (APT-1) and Acyl-protein thioesterase 2 (APT-2) are cytosolic lysophospholipids hydrolyzing enzymes. The serum activity of APT-1 may play an important role in the determination of the concentration of des-acyl ghrelin in circulation, especially under septic inflammation. APT-2/LYPLA2 is expressed both in CHO-K1 and HeLa cells and its overexpression increased the deacylation rate of single acylated GAP-43 and affected the steady-state localization of diacylated GAP-43 and H-Ras. Thus, the results demonstrate that APT-2/LYPLA2 is the protein thioesterase involved in the acylation/deacylation cycle operating in GAP-43 subcellular distribution.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human LYPLA2 protein (TMPY-02132)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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