Eotaxin/CCL11 Protein, Human, Recombinant

Name: Eotaxin/CCL11 Protein, Human, Recombinant
Brand: TargetMol
SKU: TMPJ-01001
Rating: 4.5 (1 reviews)

(Synonyms: Small-Inducible Cytokine A11, SCYA11, Eotaxin, Eosinophil Chemotactic Protein, CCL11, C-C Motif Chemokine 11) Copy Product Info

Synonyms: Small-Inducible Cytokine A11, SCYA11, Eotaxin, Eosinophil Chemotactic Protein, CCL11, C-C Motif Chemokine 11

Catalog No. TMPJ-01001 Copy Product Info

C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.

Eotaxin/CCL11 Protein, Human, Recombinant

Pack Size	Price	USA Stock	Global Stock
5 µg	$72	2-4 weeks	2-4 weeks
10 µg	$116	2-4 weeks	2-4 weeks
20 µg	$186	2-4 weeks	2-4 weeks
50 µg	$352	2-4 weeks	2-4 weeks
100 µg	$582	2-4 weeks	2-4 weeks
200 µg	$967	2-4 weeks	2-4 weeks
500 µg	$1,900	2-4 weeks	2-4 weeks
1 mg	$2,730	2-4 weeks	2-4 weeks

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P51671
Amino Acid	Gly24-Pro97
Construction	Gly24-Pro97
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Small-Inducible Cytokine A11, SCYA11, Eotaxin, Eosinophil Chemotactic Protein, CCL11, C-C Motif Chemokine 11
Research Background	C-C Motif Chemokine 11 (CCL11) is a secreted protein that belongs to the intercrine beta (chemokine CC) family. In response to the presence of allergens, CCL11 selectively recruits eosinophils, a prominent feature of allergic inflammatory reactions. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for CCL11 include CCR2, CCR3 and CCR5. However, it has been found that CCL11 has high degree selectivity for its receptor, such that they are inactive on neutrophils and monocytes, which do not express CCR3.

Chemical Properties

Molecular Weight

10 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.