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Anti-MCU Polyclonal Antibody
(Synonyms: Mitochondrial Calcium Uniporter, Coiled-coil domain-containing protein 109A, Ccdc109a, C10orf42) Copy Product Info
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Synonyms: Mitochondrial Calcium Uniporter, Coiled-coil domain-containing protein 109A, Ccdc109a, C10orf42
Catalog No. TMAB-01121 Copy Product Info
🥰Excellent
Anti-MCU Polyclonal Antibody is a Rabbit antibody targeting MCU. Anti-MCU Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB.
Anti-MCU Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-MCU Polyclonal Antibody is a Rabbit antibody targeting MCU. Anti-MCU Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | Mitochondrial Calcium Uniporter, Coiled-coil domain-containing protein 109A, Ccdc109a, C10orf42 |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes a calcium transporter that localizes to the mitochondrial inner membrane. The encoded protein interacts with mitochondrial calcium uptake 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012] |
| Immunogen | KLH conjugated synthetic peptide: human MCU |
| Antigen Species | Human |
| Gene Name | MCU |
| Gene ID | |
| Protein Name | Calcium uniporter protein, mitochondrial |
| Uniprot ID | |
| Biology Area | Cardiac metabolism,Mitochondrial markers |
| Function | Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways. Activity is regulated by MICU1 and MICU2 that stimulate and inhibit MCU activity, respectively. Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake. Involved in buffering the amplitude of systolic calcium rises in cardiomyocytes. |
| Molecular Weight | Theoretical: 40 kDa. Actual: 42 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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