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CDK5R1 Protein, Human, Recombinant (His)

Catalog No. TMPH-01170
Synonyms: CDK5 activator 1, CDK5R, NCK5A, CDK5R1, Cyclin-dependent kinase 5 activator 1, TPKII regulatory subunit, Cyclin-dependent kinase 5 regulatory subunit 1

CDK5R1 Protein, Human, Recombinant (His) is expressed in E. coli.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CDK5R1 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 284.00
100 μg 20 days $ 537.00
1 mg 20 days $ 2,300.00
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Biological Description
Technical Params
Product Properties
Description CDK5R1 Protein, Human, Recombinant (His) is expressed in E. coli.
Species Human
Expression System E. coli
Tag N-terminal 6xHis-tagged
Accession Number Q15078
Synonyms CDK5 activator 1, CDK5R, NCK5A, CDK5R1, Cyclin-dependent kinase 5 activator 1, TPKII regulatory subunit, Cyclin-dependent kinase 5 regulatory subunit 1
Amino Acid AQPPPAQPPAPPASQLSGSQTGGSSSVKKAPHPAVTSAGTPKRVIVQASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFLYMLCRDVISSEVGSDHELQAVLLTCLYLSYSYMGNEISYPLKPFLVESCKEAFWDRCLSVINLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKRLLLGLDR Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Construction 99-307 aa
Protein Purity > 85% as determined by SDS-PAGE.
Molecular Weight 27.3 kDa as predicted
Formulation If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.

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Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

CDK5R1 Protein, Human, Recombinant (His) CDK5 activator 1 CDK5R NCK5A CDK5R1 Cyclin-dependent kinase 5 activator 1 TPKII regulatory subunit Cyclin-dependent kinase 5 regulatory subunit 1 recombinant recombinant-proteins proteins protein

 

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