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Fosinopril sodium

Name: Fosinopril sodium
Brand: TargetMol
SKU: T1489
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T1489Cas No. 88889-14-9

Alias SQ28555

Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug that is converted to its active metabolite fosinoprilat.

Fosinopril sodium

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Purity: 99.40%

Catalog No. T1489Alias SQ28555Cas No. 88889-14-9

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$35	In Stock	In Stock
50 mg	$61	In Stock	In Stock
100 mg	$78	In Stock	In Stock
500 mg	$188	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.40%

Color:White

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COA HNMR LCMS

Product Introduction

Fosinopril sodium AI Summary

Fosinopril sodium has been tested in multiple assays for identifying compounds that block the entry of the Ebola virus. The assay results show that this compound has AC50 values ranging from 1412.5 nM to 2240.0 nM, indicating its ability to inhibit the entry of the Ebola virus at relatively low concentrations. This suggests that Fosinopril sodium exhibits promising bioactivity in blocking the entry of the Ebola virus, making it a potential candidate for further study in antiviral drug development..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug that is converted to its active metabolite fosinoprilat.
Synonyms	SQ28555

Chemical Properties

Molecular Weight	585.65
Formula	C₃₀H₄₅NO₇P·Na
Cas No.	88889-14-9
Smiles	[Na+].CCC(=O)OC(OP(=O)(CCCCc1ccccc1)CC(=O)N1C[C@@H](C[C@H]1C([O-])=O)C1CCCCC1)C(C)C
Relative Density.	1.173

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 1 mg/mL (1.71 mM), Sonication is recommended.

H2O: 166.7 mg/mL (284.64 mM)

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.7075 mL	8.5375 mL	17.0750 mL	85.3752 mL

H2O

	1mg	5mg	10mg	50mg
5 mM	0.3415 mL	1.7075 mL	3.4150 mL	17.0750 mL
10 mM	0.1708 mL	0.8538 mL	1.7075 mL	8.5375 mL
20 mM	0.0854 mL	0.4269 mL	0.8538 mL	4.2688 mL
50 mM	0.0342 mL	0.1708 mL	0.3415 mL	1.7075 mL
100 mM	0.0171 mL	0.0854 mL	0.1708 mL	0.8538 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc