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CP-312

Name: CP-312
Brand: TargetMol
SKU: T27064
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T27064Cas No. 895470-67-4

Alias CP312, Cardioprotectant 312

CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and targeting the antioxidant response network by inducing HMOX1 expression.CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress.

CP-312

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Purity: 99.89%

Catalog No. T27064Alias CP312, Cardioprotectant 312Cas No. 895470-67-4

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$45	In Stock	In Stock
5 mg	$106	In Stock	In Stock
10 mg	$158	In Stock	In Stock
25 mg	$289	In Stock	In Stock
50 mg	$428	In Stock	In Stock
100 mg	$591	In Stock	In Stock
500 mg	$1,270	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.89%

Appearance:Solid

Color:Red

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	CP-312 (Cardioprotectant 312) is an antioxidant defense response activator that protects hiPSC-CM viability by acting through induction of heme oxygenase-1 and targeting the antioxidant response network by inducing HMOX1 expression.CP-312 protects human iPSC-derived cardiomyocytes from oxidative stress.
In vitro	CP-312 (10 µM; 2 h) demonstrated significant efficacy in protecting hiPSC-CM from acute peroxide-induced cell death, with an EC50 of 6.7 µM.[1]
Synonyms	CP312, Cardioprotectant 312

Chemical Properties

Molecular Weight	361.87
Formula	C₁₆H₁₂ClN₃OS₂
Cas No.	895470-67-4
Smiles	ClC1=CC=C(SCC(=O)NC2=NC(=CS2)C2=CC=CC=N2)C=C1
Relative Density.	1.45 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (124.35 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7634 mL	13.8171 mL	27.6342 mL	138.1712 mL
5 mM	0.5527 mL	2.7634 mL	5.5268 mL	27.6342 mL
10 mM	0.2763 mL	1.3817 mL	2.7634 mL	13.8171 mL
20 mM	0.1382 mL	0.6909 mL	1.3817 mL	6.9086 mL
50 mM	0.0553 mL	0.2763 mL	0.5527 mL	2.7634 mL
100 mM	0.0276 mL	0.1382 mL	0.2763 mL	1.3817 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc