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Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody 2

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Catalog No. TMAC-02455

Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAP2K3 (Thr222). Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody can be used in WB,IHC.

Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody 2

Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody 2

😃Good
Catalog No. TMAC-02455
Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAP2K3 (Thr222). Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3177-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAP2K3 (Thr222). Anti-Phospho-MAP2K3 (Thr222) Polyclonal Antibody can be used in WB,IHC.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-100
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of threonine 222(A-K-T(p)-M-D) derived from Human MAP2K3
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 39 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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