Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody
😃Good
Catalog No. TMAC-01041
Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CCND2 (Thr280). Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody can be used in WB.
Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody
Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody
😃Good
Catalog No. TMAC-01041
Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CCND2 (Thr280). Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $216 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View MoreResource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CCND2 (Thr280). Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-3000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase. Hypophosphorylates RB1 in early G1 phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex By similarity. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of threonine 280 (A-S-T(p)-P-T) derived from Human Cyclin D2 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 40 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Sci Citations
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody | purchase Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody | Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody cost | order Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody | Anti-Phospho-CCND2 (Thr280) Polyclonal Antibody molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.