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NECAP2 belongs to the NECAP family. The WXXF motifs mediate binding of accessory proteins to the ear-domain of AP-1, GGAs and AP-2 through hydrophobic interactions. Adaptin ear-binding coat-associated protein 2 can interacts with AP1G1 and AP2A1 components of the adapter protein complex AP-1 and AP-2. It also interacts with the GAE domain proteins GGA1, GGA2 and GGA3.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 μg | $72 | 7-10 days | |
| 10 μg | $116 | 7-10 days | |
| 20 μg | $186 | 7-10 days | |
| 50 μg | $352 | 7-10 days | |
| 100 μg | $582 | 7-10 days | |
| 200 μg | $967 | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | |
| 1 mg | $2,730 | 7-10 days |
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | NECAP2 belongs to the NECAP family. The WXXF motifs mediate binding of accessory proteins to the ear-domain of AP-1, GGAs and AP-2 through hydrophobic interactions. Adaptin ear-binding coat-associated protein 2 can interacts with AP1G1 and AP2A1 components of the adapter protein complex AP-1 and AP-2. It also interacts with the GAE domain proteins GGA1, GGA2 and GGA3. |
| Species | Human |
| Expression System | E. coli |
| Tag | N, C-6xHis |
| Accession Number | Q9NVZ3 |
| Synonyms | NECAP2,NECAP endocytosis associated protein 2,Adaptin ear-binding coat-associated protein 2 |
| Amino Acid | Met1-Phe263 |
| Construction | Met1-Phe263 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Molecular Weight | 35 KDa (reducing condition) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, 2 mM EDTA, 1 mM DTT, pH 7.4. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Shipping with blue ice. |
| Research Background | NECAP2 belongs to the NECAP family. The WXXF motifs mediate binding of accessory proteins to the ear-domain of AP-1, GGAs and AP-2 through hydrophobic interactions. Adaptin ear-binding coat-associated protein 2 can interacts with AP1G1 and AP2A1 components of the adapter protein complex AP-1 and AP-2. It also interacts with the GAE domain proteins GGA1, GGA2 and GGA3. |

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