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Anti-PDCD4 Antibody (2Z441)
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Catalog No. TMAC-03109
Alias Protein 197/15a, Programmed Cell Death Protein 4, PDCD4, Nuclear Antigen H731-Like, Neoplastic Transformation Inhibitor Protein, H731
Anti-PDCD4 Antibody (2Z441) is a Rabbit antibody targeting PDCD4. Anti-PDCD4 Antibody (2Z441) can be used in FCM,ICC,IHC,WB.
Anti-PDCD4 Antibody (2Z441)
Anti-PDCD4 Antibody (2Z441)
😃Good
Catalog No. TMAC-03109Alias Protein 197/15a, Programmed Cell Death Protein 4, PDCD4, Nuclear Antigen H731-Like, Neoplastic Transformation Inhibitor Protein, H731
Anti-PDCD4 Antibody (2Z441) is a Rabbit antibody targeting PDCD4. Anti-PDCD4 Antibody (2Z441) can be used in FCM,ICC,IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-PDCD4 Antibody (2Z441) is a Rabbit antibody targeting PDCD4. Anti-PDCD4 Antibody (2Z441) can be used in FCM,ICC,IHC,WB. |
| Synonyms | Protein 197/15a, Programmed Cell Death Protein 4, PDCD4, Nuclear Antigen H731-Like, Neoplastic Transformation Inhibitor Protein, H731 |
| Ig Type | IgG |
| Clone | 2Z441 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500; IHC: 1:50-200; ICC: 1:20-50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The transformation suppressor gene Pdcd-4 (programmed cell death gene 4) inhibits the tumor-promoter mediated transformation of mouse keratinocytes and is a potential tumor suppressor gene in the development of human lung cancer. Biochemical analysis suggests that the Pdcd-4 protein is involved in protein translation as well as in nuclear events. Pdcd-4 directly interacts with the RNA helicase eIF4A and inhibits protein synthesis by interfering with the assembly of the cap-dependent translation initiation complex. Pdcd-4 also suppresses the transactivation of AP-1 responsive promoters by c-Jun, suggesting that the transformation-suppressor activity of Pdcd-4 might be due, at least in part, to the inhibition of c-Jun activity. In addition to affecting c-Jun phosphorylation, Pdcd-4 blocks the recruitment of the co-activator p300 by c-Jun. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 52 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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