Shopping Cart

Your shopping cart is currently empty

Carbobenzoxyphenylalanine

Name: Carbobenzoxyphenylalanine
Brand: TargetMol
SKU: T20485
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

Copy Product Info

😃Good

Catalog No. T20485Cas No. 1161-13-3

Alias NSC-402059, NSC402059, NSC 402059, Carbobenzoxy-L-phenylalanine

Carbobenzoxyphenylalanine (NSC-402059) is a thermolysin inhibitor.

Carbobenzoxyphenylalanine

Copy Product Info

😃Good

Purity: 99.71%

Catalog No. T20485Alias NSC-402059, NSC402059, NSC 402059, Carbobenzoxy-L-phenylalanineCas No. 1161-13-3

Carbobenzoxyphenylalanine (NSC-402059) is a thermolysin inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 g	$29	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.71%

Appearance:solid

Color:White

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Carbobenzoxyphenylalanine (NSC-402059) is a thermolysin inhibitor.
In vitro	The protease can be inhibited by the serine specific reagents phenylmethanesulfonyl fluoride and diisopropyl fluorophosphate and the alkylating reagent, carbobenzoxyphenylalanine chloromethyl ketone, in the presence of organic solvents at 1 mM concentration.?The inhibitions of chromatin-bound protease in rat liver by these compounds are irreversible.?On the other hand, carbobenzoxyphenylalanine and p-nitrophenyl acetate were shown to be reversible inhibitors of rat liver chromatin-bound protease[1].
Synonyms	NSC-402059, NSC402059, NSC 402059, Carbobenzoxy-L-phenylalanine

Chemical Properties

Molecular Weight	299.32
Formula	C₁₇H₁₇NO₄
Cas No.	1161-13-3
Smiles	OC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1
Relative Density.	1.1441 g/cm3 (Estimated)
Sequence	Cbz-Phe-OH
Sequence Short	F

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (200.45 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3409 mL	16.7045 mL	33.4091 mL	167.0453 mL
5 mM	0.6682 mL	3.3409 mL	6.6818 mL	33.4091 mL
10 mM	0.3341 mL	1.6705 mL	3.3409 mL	16.7045 mL
20 mM	0.1670 mL	0.8352 mL	1.6705 mL	8.3523 mL
50 mM	0.0668 mL	0.3341 mL	0.6682 mL	3.3409 mL
100 mM	0.0334 mL	0.1670 mL	0.3341 mL	1.6705 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc