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Carbobenzoxyphenylalanine

Name: Carbobenzoxyphenylalanine
Brand: TargetMol
SKU: T20485
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T20485Cas No. 1161-13-3

Alias NSC-402059, NSC402059, NSC 402059, Carbobenzoxy-L-phenylalanine

Carbobenzoxyphenylalanine (NSC-402059) is a thermolysin inhibitor.

Carbobenzoxyphenylalanine

🥰Excellent

Purity: 99.71%

Catalog No. T20485Alias NSC-402059, NSC402059, NSC 402059, Carbobenzoxy-L-phenylalanineCas No. 1161-13-3

Carbobenzoxyphenylalanine (NSC-402059) is a thermolysin inhibitor.

Pack Size	Price	Availability	Quantity
1 g	$29	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.71%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Carbobenzoxyphenylalanine (NSC-402059) is a thermolysin inhibitor.
In vitro	The protease can be inhibited by the serine specific reagents phenylmethanesulfonyl fluoride and diisopropyl fluorophosphate and the alkylating reagent, carbobenzoxyphenylalanine chloromethyl ketone, in the presence of organic solvents at 1 mM concentration.?The inhibitions of chromatin-bound protease in rat liver by these compounds are irreversible.?On the other hand, carbobenzoxyphenylalanine and p-nitrophenyl acetate were shown to be reversible inhibitors of rat liver chromatin-bound protease[1].
Synonyms	NSC-402059, NSC402059, NSC 402059, Carbobenzoxy-L-phenylalanine

Chemical Properties

Molecular Weight	299.32
Formula	C₁₇H₁₇NO₄
Cas No.	1161-13-3
Smiles	OC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1
Relative Density.	1.1441 g/cm3 (Estimated)
Color	White
Appearance	solid

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (200.45 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3409 mL	16.7045 mL	33.4091 mL	167.0453 mL
5 mM	0.6682 mL	3.3409 mL	6.6818 mL	33.4091 mL
10 mM	0.3341 mL	1.6705 mL	3.3409 mL	16.7045 mL
20 mM	0.1670 mL	0.8352 mL	1.6705 mL	8.3523 mL
50 mM	0.0668 mL	0.3341 mL	0.6682 mL	3.3409 mL
100 mM	0.0334 mL	0.1670 mL	0.3341 mL	1.6705 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc