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Lipoxamycin hemisulfate

🥰Excellent
Catalog No. T26308Cas No. 11075-87-9
Alias U-26146D, U26146D, U 26146D, Lipoxamycin, sulfate (2:1), Lipoxamycin

Lipoxamycin hemisulfate (Lipoxamycin) is an inhibitor of serine palmitoyltransferase (IC50 = 21 nM) with antifungal activity.

Lipoxamycin hemisulfate
Other Forms of Lipoxamycin hemisulfate:

Lipoxamycin hemisulfate

🥰Excellent
Purity: 99.93%
Catalog No. T26308Alias U-26146D, U26146D, U 26146D, Lipoxamycin, sulfate (2:1), LipoxamycinCas No. 11075-87-9
Lipoxamycin hemisulfate (Lipoxamycin) is an inhibitor of serine palmitoyltransferase (IC50 = 21 nM) with antifungal activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$50In StockIn Stock
2 mg$72In StockIn Stock
5 mg$118In StockIn Stock
10 mg$198In StockIn Stock
25 mg$446In StockIn Stock
50 mg$762In StockIn Stock
100 mg$1,290-In Stock
200 mg$1,730-In Stock
1 mL x 10 mM (in DMSO)$128In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.93%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
Lipoxamycin hemisulfate (Lipoxamycin) is an inhibitor of serine palmitoyltransferase (IC50 = 21 nM) with antifungal activity.
In vitro
Lipoxamycin hemisulfate shows antifungal activity against a panel of human pathogenic fungi with better potency against some of the Candida species (MIC = 0.25-16 µg/mL)[1].
In vivo
In Chinese hamster ovary cell mutant, Lipoxamycin hemisulfate is highly toxic in mice when applied subeutaneously or topically[1].
SynonymsU-26146D, U26146D, U 26146D, Lipoxamycin, sulfate (2:1), Lipoxamycin
Chemical Properties
Molecular Weight843.08
FormulaC38H74N4O14S
Cas No.11075-87-9
SmilesCC(C)CCCC(=O)CCCCCCC(=O)CCN(C(=O)[C@H](CO)N)O.CC(C)CCCC(=O)CCCCCCC(=O)CCN(C(=O)[C@H](CO)N)O.OS(=O)(=O)O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 36 mg/mL (42.7 mM), Sonication and heating to 60℃ are recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.1861 mL5.9306 mL11.8613 mL59.3064 mL
5 mM0.2372 mL1.1861 mL2.3723 mL11.8613 mL
10 mM0.1186 mL0.5931 mL1.1861 mL5.9306 mL
20 mM0.0593 mL0.2965 mL0.5931 mL2.9653 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Lipoxamycin, SulfateLipoxamycin HemisulfateFungal2:1
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