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Osteogenic Growth Peptide (10-14) acetate

Catalog No. T37603L

Synonyms: Osteogenic Growth Peptide (10-14) acetate(105250-85-9 Free base)

Osteogenic Growth Peptide (10-14) acetate (Osteogenic Growth Peptide) is a Src inhibitor and an effective mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acetate is responsible for the binding to the OGP receptor and activates an intracell

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Osteogenic Growth Peptide (10-14) acetate Chemical Structure

Osteogenic Growth Peptide (10-14) acetate, CAS N/A

Pack Size	Availability	Price/USD
1 mg	In stock	$ 227.00
2 mg	In stock	$ 397.00
5 mg	In stock	$ 572.00
10 mg	In stock	$ 818.00
25 mg	In stock	$ 1,250.00
50 mg	In stock	$ 1,690.00
100 mg	In stock	$ 2,280.00
1 mL * 10 mM (in DMSO)	In stock	$ 773.00

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Purity: 98.69%

Biological Description

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Storage & Solubility Information

Description	Osteogenic Growth Peptide (10-14) acetate (Osteogenic Growth Peptide) is a Src inhibitor and an effective mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acetate is responsible for the binding to the OGP receptor and activates an intracell
In vitro	In fibroblast and osteoblast cell lines, Osteogenic Growth Peptide (10-14) acetate induced proliferation and differentiation[2]. Osteogenic Growth Peptide (10-14) acetate induced TPO-primed M07-e cells differentiation through RhoA/TGFβ1/SFKs signalling pathway[3].
In vivo	In mice and rats, Osteogenic Growth Peptide (10-14) acetate increased bone formation and trabecular bone density and stimulated fracture healing[4].

Synonyms	Osteogenic Growth Peptide (10-14) acetate(105250-85-9 Free base)
Molecular Weight	559.57
Formula	C26H33N5O9

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 5.6 mg/mL (10 mM)

References and Literature

1. Chen Z, et al. Regulation of endochondral ossification by osteogenic growth peptide C-terminal pentapeptide [OGP(10-14)]. Protein Pept Lett. 2009;16(9):1074-1080. 2. Fazzi R, et al. Bone and bone-marrow interactions: haematological activity of osteoblastic growth peptide (OGP)-derived carboxy-terminal pentapeptide. Mobilizing properties on white blood cells and peripheral blood stem cells in mice. Leuk Res. 2002;26(1) 3. Battolla B, et al. The small peptide OGP(10-14) reduces proliferation and induces differentiation of TPO-primed M07-e cells through RhoA/TGFbeta1/SFK pathway. Med Sci Monit. 2011;17(1):SC1-SC5. 4. Chen YC, et al. Bioactive pseudopeptidic analogues and cyclostereoisomers of osteogenic growth peptide C-terminal pentapeptide, OGP(10-14). J Med Chem. 2002;45(8):1624-1632.

Related compound libraries

This product is contained In the following compound libraries：

Tyrosine Kinase Inhibitor Library Inhibitor Library Peptide Compound Library Anti-Pancreatic Cancer Compound Library Kinase Inhibitor Library Bioactive Compound Library Bioactive Compounds Library Max Angiogenesis related Compound Library Anti-Cancer Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Osteogenic Growth Peptide (10-14) acetate Angiogenesis Tyrosine Kinase/Adaptors Src Osteogenic Growth Peptide (1014) acetate Osteogenic Growth Peptide Acetate Osteogenic Growth Peptide (10-14) acetate(105250-85-9 Free base) Osteogenic Growth Peptide Osteogenic Growth Peptide (10 14) acetate inhibitor inhibit

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