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Osteogenic Growth Peptide (10-14) acetate

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Catalog No. T37603L
Alias Osteogenic Growth Peptide (10-14) acetate(105250-85-9 Free base)

Osteogenic Growth Peptide (10-14) acetate (Osteogenic Growth Peptide) is a Src inhibitor and an effective mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acetate is responsible for the binding to the OGP receptor and activates an intracell

Osteogenic Growth Peptide (10-14) acetate

Osteogenic Growth Peptide (10-14) acetate

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Purity: 98.69%
Catalog No. T37603LAlias Osteogenic Growth Peptide (10-14) acetate(105250-85-9 Free base)
Osteogenic Growth Peptide (10-14) acetate (Osteogenic Growth Peptide) is a Src inhibitor and an effective mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acetate is responsible for the binding to the OGP receptor and activates an intracell
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$227-In Stock
2 mg$397-In Stock
5 mg$572-In Stock
10 mg$818-In Stock
25 mg$1,250-In Stock
50 mg$1,690-In Stock
100 mg$2,280-In Stock
1 mL x 10 mM (in DMSO)$773-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:98.69%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Osteogenic Growth Peptide (10-14) acetate (Osteogenic Growth Peptide) is a Src inhibitor and an effective mitogen and stimulator of osteogenesis and hematopoiesis. Osteogenic Growth Peptide (10-14) acetate is responsible for the binding to the OGP receptor and activates an intracell
In vitro
In fibroblast and osteoblast cell lines, Osteogenic Growth Peptide (10-14) acetate induced proliferation and differentiation[2]. Osteogenic Growth Peptide (10-14) acetate induced TPO-primed M07-e cells differentiation through RhoA/TGFβ1/SFKs signalling pathway[3].
In vivo
In mice and rats, Osteogenic Growth Peptide (10-14) acetate increased bone formation and trabecular bone density and stimulated fracture healing[4].
SynonymsOsteogenic Growth Peptide (10-14) acetate(105250-85-9 Free base)
Chemical Properties
Molecular Weight559.57
FormulaC26H33N5O9
SmilesO=C(NCC(NCC(O)=O)=O)[C@@H](NC(CNC([C@@H](N)CC1=CC=C(O)C=C1)=O)=O)CC2=CC=CC=C2.CC(O)=O
SequenceTyr-Gly-Phe-Gly-Gly
Sequence ShortYGFGG
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 5.6 mg/mL (10.01 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7871 mL8.9354 mL17.8709 mL89.3543 mL
5 mM0.3574 mL1.7871 mL3.5742 mL17.8709 mL
10 mM0.1787 mL0.8935 mL1.7871 mL8.9354 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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