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PD 0299685

Name: PD 0299685
Brand: TargetMol
SKU: T68125L
Rating: 4.5 (1 reviews)

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Catalog No. T68125LCas No. 313651-33-1

Alias PF-299685, PD-299,685

PD 0299685 is a potent α2δ ligand of the Ca2+ channel for the treatment of interstitial cystitis.

PD 0299685

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Catalog No. T68125LAlias PF-299685, PD-299,685Cas No. 313651-33-1

PD 0299685 is a potent α2δ ligand of the Ca2+ channel for the treatment of interstitial cystitis.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$195	Inquiry	Inquiry
5 mg	$483	Inquiry	Inquiry
10 mg	$692	Inquiry	Inquiry
25 mg	$1,080	Inquiry	Inquiry
50 mg	$1,490	Inquiry	Inquiry
100 mg	$1,970	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	PD 0299685 is a potent α2δ ligand of the Ca2+ channel for the treatment of interstitial cystitis.
Synonyms	PF-299685, PD-299,685

Chemical Properties

Molecular Weight	187.28
Formula	C₁₀H₂₁NO₂
Cas No.	313651-33-1
Smiles	[C@H](C[C@@H](CCC)C)(CC(O)=O)CN
Relative Density.	0.972 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (293.68 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.3396 mL	26.6980 mL	53.3960 mL	266.9799 mL
5 mM	1.0679 mL	5.3396 mL	10.6792 mL	53.3960 mL
10 mM	0.5340 mL	2.6698 mL	5.3396 mL	26.6980 mL
20 mM	0.2670 mL	1.3349 mL	2.6698 mL	13.3490 mL
50 mM	0.1068 mL	0.5340 mL	1.0679 mL	5.3396 mL
100 mM	0.0534 mL	0.2670 mL	0.5340 mL	2.6698 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc