Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PERK-IN-5 is a highly selective, potent, orally active inhibitor of the protein kinase R-like endoplasmic reticulum (ER) kinase (PERK) that acts on PERK (IC50: 2 nM) and p-eIF2α (IC50: 9 nM). PERK-IN-5 significantly inhibited tumour growth in the 786-O renal cell carcinoma xenograft tumour model.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,990.00 | |
50 mg | 6-8 weeks | $ 3,230.00 |
Description | PERK-IN-5 is a highly selective, potent, orally active inhibitor of the protein kinase R-like endoplasmic reticulum (ER) kinase (PERK) that acts on PERK (IC50: 2 nM) and p-eIF2α (IC50: 9 nM). PERK-IN-5 significantly inhibited tumour growth in the 786-O renal cell carcinoma xenograft tumour model. |
Molecular Weight | 468.5 |
Formula | C25H26F2N4O3 |
CAS No. | 2616821-91-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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PERK-IN-5 2616821-91-9 inhibitor inhibit