APRIL/TNFSF13 Protein, Mouse, Recombinant

Name: APRIL/TNFSF13 Protein, Mouse, Recombinant
Brand: TargetMol
SKU: TMPS-00159
Rating: 4.5 (1 reviews)

(Synonyms: TRDL-1 alpha, TNFSF13, A proliferating-inducing ligand) Copy Product Info

Synonyms: TRDL-1 alpha, TNFSF13, A proliferating-inducing ligand

Catalog No. TMPS-00159 Copy Product Info

APRIL/TNFSF13 Protein, Mouse, Recombinant is expressed in E. coli. The accession number is Q9D777.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$85	7-10 days	7-10 days
10 µg	$138	7-10 days	7-10 days
20 µg	$189	7-10 days	7-10 days
50 µg	$297	7-10 days	7-10 days
100 µg	$489	7-10 days	7-10 days
200 µg	$816	7-10 days	7-10 days
500 µg	$1,580	7-10 days	7-10 days
1 mg	$2,680	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its ability to induce cell proliferation of RPMI 8226 Cells.
Description	APRIL/TNFSF13 Protein, Mouse, Recombinant is expressed in E. coli. The accession number is Q9D777.
Species	Mouse
Expression System	E. coli
Tag	Tag Free
Accession Number	Q9D777
Construction	Arg50-Leu241
Protein Purity	> 95% as determined by SDS-PAGE; > 95% as determined by HPLC
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized after extensive dialysis against 20 mM acetic acid.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	TRDL-1 alpha, TNFSF13, A proliferating-inducing ligand
Research Background	A Proliferation-inducing Ligand (April)) also known as TNSF13A, Tall-2, and TRDL-1, is a member of the TNF ligand (TNFL) superfamily. April is most similar to B-cell activation factor (BAFF) with which it shares 30% sequence identity, compete for two receptors, TACI and BCMA. APRIL is expressed at low levels in lymphoid tissue and is over-expressed by a number of tumors. April has a proliferative effect on both normal and tumor cell lines in vitro and in vivo. APRIL seems to be involved in the regulation of death and proliferation of tumor cells, but there are still contradictory findings regarding its overall biological effects.

Chemical Properties

Molecular Weight

~21.9 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.