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TargetMol | Compound Library

Alkaloid Natural Product Library

Catalog No. L6110

Alkaloids are a class of naturally occurring organic compounds that mostly contain basic nitrogen atoms, and mainly produced by plant. A large amount of research have found that alkaloids have a wide range of pharmacological activities including antimalarial (e.g. quinine), antiasthma, anticancer (e.g. homoharringtonine), cholinomimetic (e.g. galantamine), vasodilatory (e.g. vincamine), antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and antihyperglycemic activities (e.g. piperine). Many have found use in traditional or modern medicine, or as starting points for drug discovery. As research in alkaloids advances, alkaloids would play an important and visible role in modern drug development and provide a continuing source of novel drug leads.

TargetMol's Alkaloid Natural Product Library carefully collects 500 alkaloids derived from plants, including Aconite, Periwinkle, Camptotheca acuminate, Belladonna, Coptis chinensis, etc. They have anticancer, anti-inflammatory, anti-oxidative, and neuroprotective effects. For example, vinca alkaloids obtained from Madagascar periwinkle plant are important for being cancer fighters and are the second-most-used class of cancer drugs and will stay among the original caner therapies. Lycorine, one of the main alkaloids of the Amaryllidaceae family, was found to be responsible for the pronounced antiviral and antibacterial activity of the crude extracts from the roots and leaves of Clivia miniata Regel. Tetrahydropalmatine, an isoquinoline alkaloid that is considered the active ingredient of Corydalis yanhusuo, has significant analgesic effects.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L6110

Alkaloid Natural Product Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 500 natural alkaloids can be used for high throughput and high content screening;
  • Most compounds have confirmed bioactivity with anticancer, anti-inflammatory, anti-oxidative, and neuroprotective effects;
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
Autophagy
Endogenous Metabolite
Antibacterial
NF-κB
Parasite
AChR
Cholinesterase (ChE)
Antifungal
ROS
p38 MAPK
Antibiotic
Topoisomerase
Interleukin
Akt
Cytochromes P450
Calcium Channel
Potassium Channel
PI3K
Adrenergic Receptor
Antioxidant
Reactive Oxygen Species
5-HT Receptor
Caspase
Influenza Virus
Microtubule Associated
Sodium Channel
DNA/RNA Synthesis
ERK
Anti-infection
Dopamine Receptor
TNF
HIV Protease
Ferroptosis
Bcl-2 Family
Drug Metabolite
PDE
NO Synthase
JNK
COX
Virus Protease
Adenosine Receptor
P-gp
CDK
AMPK
GABA Receptor
IDO
STAT
Indoleamine 2,3-Dioxygenase (IDO)
Nrf2
TGF-beta/Smad
MDM-2/p53
TRP/TRPV Channel
Beta Amyloid
MMP
Opioid Receptor
TLR
Beta-Secretase
PARP
Platelet aggregation
Dehydrogenase
PKC
IL Receptor
RAAS
Histamine Receptor
Mitophagy
SARS-CoV
MAO
BACE
Antiviral
NOD-like Receptor (NLR)
Monoamine Oxidase
P2X Receptor
Antifection
FAK
Angiotensin-converting Enzyme (ACE)
PERK
Nucleoside Antimetabolite/Analog
E1/E2/E3 Enzyme
glycosidase
mTOR
HDAC
NOS
Cadherin
ADC Cytotoxin
PKA
Serotonin Transporter
Glucosidase
Smo
Hedgehog/Smoothened
cAMP
Lipoxygenase
EGFR
HIF
ROS Kinase
NADPH
RANKL/RANK
MEK
Fatty Acid Synthase
PAD
Aurora Kinase
PGE Synthase
MAPK
HIF/HIF Prolyl-Hydroxylase
ATPase
Wnt/beta-catenin
iGluR
FAAH
Imidazoline Receptor
Glutathione Peroxidase
Aryl Hydrocarbon Receptor
Prostaglandin Receptor
Proteasome
GSK-3
LDLR
JAK
HSP
IκB/IKK
Phospholipase
FOXO
GPCR
Arginase
DYRK
c-Myc
PAK
PAI-1
GST
Reverse Transcriptase
OCT
Raf
FLT
LPL Receptor
MRP
RIP kinase
Bcr-Abl
BCRP
Aquaporin
MicroRNA
PPAR
Cell Cycle Arrest
VEGFR
Immunology/Inflammation related
OAT
RSV
S1P Receptor
Hydrogenase
Src
Tyrosine Kinases
Adiponectin Receptor
Monoamine Transporter
PDGFR
HSV
IGF-1R
DNA
Casein Kinase
Chloride channel
Proton pump
Monocarboxylate transporter
HCV Protease
Serine/threonin kinase
Cysteine Protease
Leukotriene Receptor
DNA gyrase
PTEN
OXPHOS
STING
Pyroptosis
Tyrosinase
p53
MLK

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