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TargetMol | Compound Library

Alkaloid Natural Product Library

Catalog No. L6110

Alkaloids are a class of naturally occurring organic compounds that mostly contain basic nitrogen atoms, and mainly produced by plant. A large amount of research have found that alkaloids have a wide range of pharmacological activities including antimalarial (e.g. quinine), antiasthma, anticancer (e.g. homoharringtonine), cholinomimetic (e.g. galantamine), vasodilatory (e.g. vincamine), antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and antihyperglycemic activities (e.g. piperine). Many have found use in traditional or modern medicine, or as starting points for drug discovery. As research in alkaloids advances, alkaloids would play an important and visible role in modern drug development and provide a continuing source of novel drug leads.

TargetMol's Alkaloid Natural Product Library carefully collects 500 alkaloids derived from plants, including Aconite, Periwinkle, Camptotheca acuminate, Belladonna, Coptis chinensis, etc. They have anticancer, anti-inflammatory, anti-oxidative, and neuroprotective effects. For example, vinca alkaloids obtained from Madagascar periwinkle plant are important for being cancer fighters and are the second-most-used class of cancer drugs and will stay among the original caner therapies. Lycorine, one of the main alkaloids of the Amaryllidaceae family, was found to be responsible for the pronounced antiviral and antibacterial activity of the crude extracts from the roots and leaves of Clivia miniata Regel. Tetrahydropalmatine, an isoquinoline alkaloid that is considered the active ingredient of Corydalis yanhusuo, has significant analgesic effects.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L6110

Alkaloid Natural Product Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 500 natural alkaloids can be used for high throughput and high content screening;
  • Most compounds have confirmed bioactivity with anticancer, anti-inflammatory, anti-oxidative, and neuroprotective effects;
  • Detailed compound information with structure, target, and biological activity description;
  • NMR and HPLC validated to ensure high purity and quality.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Apoptosis
Autophagy
Endogenous Metabolite
Antibacterial
Parasite
AChR
NF-κB
Cholinesterase (ChE)
Antifungal
Topoisomerase
Antibiotic
Antioxidant
Calcium Channel
Adrenergic Receptor
Potassium Channel
Reactive Oxygen Species
Cytochromes P450
5-HT Receptor
Microtubule Associated
Sodium Channel
Influenza Virus
Anti-infection
Dopamine Receptor
DNA/RNA Synthesis
p38 MAPK
Caspase
TNF
HIV Protease
Virus Protease
PDE
Akt
Bcl-2 Family
Drug Metabolite
Ferroptosis
PI3K
Adenosine Receptor
ERK
COX
Interleukin
GABA Receptor
JNK
TRP/TRPV Channel
IDO
Opioid Receptor
Indoleamine 2,3-Dioxygenase (IDO)
P-gp
IL Receptor
TGF-beta/Smad
Beta Amyloid
STAT
AMPK
Platelet aggregation
NO Synthase
NOS
BACE
RAAS
Histamine Receptor
Mitophagy
PARP
Nucleoside Antimetabolite/Analog
PKC
MAO
E1/E2/E3 Enzyme
Antifection
MMP
Beta-Secretase
Antiviral
SARS-CoV
TLR
Nrf2
HDAC
MDM-2/p53
FAK
Monoamine Oxidase
ADC Cytotoxin
ATPase
Dehydrogenase
PKA
Serotonin Transporter
RANKL/RANK
iGluR
P2X Receptor
Glucosidase
ROS
Smo
Fatty Acid Synthase
Hedgehog/Smoothened
FAAH
Angiotensin-converting Enzyme (ACE)
Aurora Kinase
cAMP
Lipoxygenase
EGFR
PGE Synthase
Prostaglandin Receptor
GST
HIF
HIF/HIF Prolyl-Hydroxylase
Imidazoline Receptor
GPCR
Proteasome
Chloride channel
MicroRNA
Monocarboxylate transporter
Hydrogenase
HCV Protease
Src
Arginase
LPL Receptor
DYRK
NADPH
PERK
Glutathione Peroxidase
GSK-3
OCT
MRP
Tyrosine Kinases
Cell Cycle Arrest
Serine/threonin kinase
Cysteine Protease
Leukotriene Receptor
VEGFR
LDLR
Aryl Hydrocarbon Receptor
Immunology/Inflammation related
Adiponectin Receptor
Bcr-Abl
Raf
CDK
DNA gyrase
Monoamine Transporter
PDGFR
PAK
HSV
PTEN
PAD
Cadherin
IGF-1R
CaMK
DNA
BCRP
OXPHOS
MAPK
HSP
RSV
IκB/IKK
Reverse Transcriptase
Phospholipase
MEK
FLT
ROS Kinase
p53
S1P Receptor

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