LDLR Protein, Human, Recombinant (His & Avi)

Name: LDLR Protein, Human, Recombinant (His & Avi)
Brand: TargetMol
SKU: TMPK-00402
Price: 56 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: LDLR, LDLCQ2, LDL receptor, LDL R, FHC, FH) Copy Product Info

Synonyms: LDLR, LDLCQ2, LDL receptor, LDL R, FHC, FH

Catalog No. TMPK-00402 Copy Product Info

The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. LDLR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 87.6 kDa and the accession number is P01130-1.

LDLR Protein, Human, Recombinant (His & Avi)

Pack Size	Price	USA Stock	Global Stock
5 µg	$56	-	In Stock
10 µg	$88	-	In Stock
20 µg	$143	-	In Stock
50 µg	$278	-	In Stock
100 µg	$465	-	In Stock
200 µg	$839	7-10 days	7-10 days
500 µg	$1,850	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:> 95%

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Human LDLR, His Tag immobilized on CM5 Chip can bind Human PCSK9, His Tag with an affinity constant of 0.35 nM as determined in SPR assay.
Description	The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. LDLR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 87.6 kDa and the accession number is P01130-1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His-Avi
Accession Number	P01130-1
Construction	Ala22-Arg788
Protein Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	LDLR, LDLCQ2, LDL receptor, LDL R, FHC, FH
Research Background	The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles.

Chemical Properties

Molecular Weight

87.6 kDa (predicted). Due to glycosylation, the protein migrates to 110-130 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.