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Anti-GADD45A Polyclonal Antibody
(Synonyms: growth arrest and DNA-damage-inducible, α, growth arrest and DNA-damage-inducible, alpha, GADD45, DDIT1) Copy Product Info
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Synonyms: growth arrest and DNA-damage-inducible, α, growth arrest and DNA-damage-inducible, alpha, GADD45, DDIT1
Catalog No. TMAB-00733 Copy Product Info
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Anti-GADD45A Polyclonal Antibody is a Rabbit antibody targeting GADD45A. Anti-GADD45A Polyclonal Antibody can be used in FCM,ICC/IF,IF,IHC-Fr,IHC-P,WB.
Anti-GADD45A Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GADD45A Polyclonal Antibody is a Rabbit antibody targeting GADD45A. Anti-GADD45A Polyclonal Antibody can be used in FCM,ICC/IF,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | growth arrest and DNA-damage-inducible, α, growth arrest and DNA-damage-inducible, alpha, GADD45, DDIT1 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Pig,Cow) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; FCM: 3ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53 dependent and independent mechanisms. |
| Immunogen | KLH conjugated synthetic peptide: human GADD45 |
| Antigen Species | Human |
| Gene Name | GADD45A |
| Gene ID | |
| Protein Name | Growth arrest and DNA damage-inducible protein GADD45 alpha |
| Uniprot ID | |
| Biology Area | Base Excision Repair |
| Function | In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity. Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. |
| Molecular Weight | Theoretical: 18 kDa. Actual: 18 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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