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Anti-Renin Antibody (5W254)
😃Good
Catalog No. TMAY-01382
Alias renin, REN, HNFJ2, FLJ10761
Anti-Renin Antibody (5W254) is a Mouse antibody targeting Renin. Anti-Renin Antibody (5W254) can be used in ELISA,IHC-P.
Anti-Renin Antibody (5W254)
Anti-Renin Antibody (5W254)
😃Good
Catalog No. TMAY-01382Alias renin, REN, HNFJ2, FLJ10761
Anti-Renin Antibody (5W254) is a Mouse antibody targeting Renin. Anti-Renin Antibody (5W254) can be used in ELISA,IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Renin Antibody (5W254) is a Mouse antibody targeting Renin. Anti-Renin Antibody (5W254) can be used in ELISA,IHC-P. |
| Synonyms | renin, REN, HNFJ2, FLJ10761 |
| Ig Type | Mouse IgG2b |
| Clone | 5W254 |
| Reactivity | Human |
| Specificity | Human Renin |
| Verified Activity | Immunochemical staining of human RENIN in human kidney (from 2 donors) with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections). |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000; IHC-P: 1:50-1:200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Renin (rh Renin; TMPY-00908; NP_000528.1; Met 1-Arg 406). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Renin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. androgen and thyroid hormones influence levels of Renin-1 in mouse submandibular gland (SMG) primarily by regulating the amount of Renin-1 mRNA available for translation. Renin-1 is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. It is expressed at relatively low levels in mouse SMG and kidney. Ren-2 is expressed at high levels in the mouse SMG and at very low levels, if at all, in the kidney. Ren-1 and Ren-2 are closely linked on mouse chromosome 1, show extensive homology in coding and noncoding regions and provide a model for studying the regulation of gene expression. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human Renin protein (TMPY-00908) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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