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Anti-HER4/ERBB4 Antibody (8W756)

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Catalog No. TMAC-01813

Anti-HER4/ERBB4 Antibody (8W756) is a Mouse antibody targeting HER4/ERBB4. Anti-HER4/ERBB4 Antibody (8W756) can be used in WB,IP,IF,IHC-P,FCM.

Anti-HER4/ERBB4 Antibody (8W756)

Anti-HER4/ERBB4 Antibody (8W756)

😃Good
Catalog No. TMAC-01813
Anti-HER4/ERBB4 Antibody (8W756) is a Mouse antibody targeting HER4/ERBB4. Anti-HER4/ERBB4 Antibody (8W756) can be used in WB,IP,IF,IHC-P,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4287-10 days
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Product Introduction

Bioactivity
Description
Anti-HER4/ERBB4 Antibody (8W756) is a Mouse antibody targeting HER4/ERBB4. Anti-HER4/ERBB4 Antibody (8W756) can be used in WB,IP,IF,IHC-P,FCM.
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate); FCM: 1 μg per 1 x 106 cells
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe EGF receptor family comprises several related receptor tyrosine kinases that are frequently overexpressed in a variety of carcinomas. Members of this receptor family include EGFR (HER1), Neu (ErbB-2, HER2), ErbB-3 (HER3) and ErbB-4 (HER4), which form either homodimers or heterodimers upon ligand binding. The gene encoding ErbB-4 is expressed as a full length protein, which produces a short membrane-anchored cytoplasmic domain fragment and a long ectodomain fragment. The short fragment is heavily tyrosine phosphorylated and possesses tyrosine kinase catalytic activity toward an exogenous substrate. Proteolytic cleavage of ErbB-4 is promoted by the binding of heregulin. ErbB-4 is involved in cell proliferation and differentiation and its expression is highest in breast carcinoma cell lines, normal skeletal muscle, heart, pituitary, brain and cerebellum.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Amino acids 1280-1308 at C-terminus of ErbB-4 of human origin
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 180 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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