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Beta Klotho Protein, Mouse, Recombinant (His)
(Synonyms: β-klotho, βKlotho, β Klotho, MGC142213, klotho β like, Klotho β, klotho beta like, Klotho beta, KLB, BKL, beta-klotho, betaKlotho) Copy Product InfoSynonyms: β-klotho, βKlotho, β Klotho, MGC142213, klotho β like, Klotho β, klotho beta like, Klotho beta, KLB, BKL, beta-klotho, betaKlotho
Catalog No. TMPK-01150 Copy Product Info
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the accession number is Q99N32-1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $61 | - | In Stock | |
| 10 μg | $96 | - | In Stock | |
| 20 μg | $156 | - | In Stock | |
| 50 μg | $297 | - | In Stock | |
| 100 μg | $511 | 7-10 days | 7-10 days | |
| 200 μg | $925 | 7-10 days | 7-10 days | |
| 500 μg | $2,030 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:SDS-PAGE: > 90%; SEC-HPLC: > 90%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Human FGFR4, hFc Tag captured on CM5 Chip via Protein A can bind Mouse Beta Klotho, His Tag with an affinity constant of 36.97 nM as determined in SPR assay. |
| Description | Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the accession number is Q99N32-1. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | Q99N32-1 |
| Construction | Phe53-Pro994 |
| Protein Purity | > 90% as determined by Tris-Bis PAGE; > 90% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Stability & Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | β-klotho, βKlotho, β Klotho, MGC142213, klotho β like, Klotho β, klotho beta like, Klotho beta, KLB, BKL, beta-klotho, betaKlotho |
| Research Background |
| Molecular Weight | 109.91 kDa (predicted). Due to glycosylation, the protein migrates to 120-130 kDa based on Tris-Bis PAGE result. |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: Beta Klotho Protein, Mouse, Recombinant (His) chemical structure | Beta Klotho Protein, Mouse, Recombinant (His) molecular weight
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