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TargetMol | Compound Library

Anti-Cardiovascular Disease Compound Library

Catalog No. L5400

Cardiovascular disease generally refers to all types of diseases that affect the heart or blood vessels, including coronary heart disease (clogged arteries), which can cause heart attacks, stroke, congenital heart defects and peripheral artery disease, and is the leading cause of death for men and women in the U.S. Different types of cardiovascular diseases have different mechanisms of pathogenesis. Antioxidants, lipid-lowering agents, anti-ischemic drugs, and platelet aggregation inhibitors all can reduce cardiovascular disease risk. Some natural products can inhibit the gene expression of cell adhesion molecules, cytokine, and chemokine, inhibit the function of platelet, enhance the release of nitric oxide by endothelial cells, and inhibit the contraction of smooth muscle.

A unique collection of 1793 cardiovascular diseases related compounds by TargetMol can be used for cardiovascular diseases related research and high throughput and high content screening for new drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L5400

Anti-Cardiovascular Disease Compound Library

sizeIn stock

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1793 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved by FDA, EMA, or NMPA;
  • Covers various major targets including membrane transporter, ion channel, etc.; Effect tool for research in cardiovascular disease.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Supporting Files | TargetMol Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (60.2 MB)

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Adrenergic Receptor
Apoptosis
Calcium Channel
PDE
Autophagy
VEGFR
Endogenous Metabolite
COX
Sodium Channel
Potassium Channel
NF-κB
Antibacterial
5-HT Receptor
TNF
AChR
ROS
PDGFR
RAAS
Dopamine Receptor
Parasite
Angiotensin-converting Enzyme (ACE)
FGFR
c-Kit
IL Receptor
p38 MAPK
Histamine Receptor
Interleukin
PARP
Histone Acetyltransferase
FLT
Reactive Oxygen Species
PPAR
Drug Metabolite
ERK
Akt
CDK
NO Synthase
Cytochromes P450
HMG-CoA Reductase
EGFR
PKC
Adenosine Receptor
Factor Xa
DNA/RNA Synthesis
Antifungal
JAK
Epigenetic Reader Domain
BACE
Antioxidant
PI3K
Antibiotic
Influenza Virus
Carbonic Anhydrase
IGF-1R
Prostaglandin Receptor
Src
Ferroptosis
c-Met/HGFR
Mitophagy
ATPase
Caspase
Norepinephrine
HIV Protease
JNK
Beta-Secretase
c-RET
TRP/TRPV Channel
Thrombin
Nrf2
PKA
Phospholipase
Glucocorticoid Receptor
STAT
NOD-like Receptor (NLR)
P2Y Receptor
SARS-CoV
CaMK
Beta Amyloid
Wnt/beta-catenin
iGluR
Cholinesterase (ChE)
HDAC
P-gp
GABA Receptor
GSK-3
Lipoxygenase
Mitochondrial Metabolism
Proteasome
Integrin
AMPK
Raf
Virus Protease
Guanylate cyclase
MRP
MEK
Anti-infection
Monoamine Oxidase
NMDAR
c-Fms
Bcr-Abl
Dehydrogenase
ROCK
Tyrosine Kinases
Hydroxylase
Tyrosinase
Serine Protease
Serotonin Transporter
LDLR
Aurora Kinase
NADPH
Proton pump
Glutathione Peroxidase
Serine/threonin kinase
Topoisomerase
Acetyl-CoA Carboxylase
Liver X Receptor
MAO
NOD
MMP
Tie-2
IκB/IKK
Microtubule Associated
CETP
PERK
Nucleoside Antimetabolite/Analog
HSV
GluR
mTOR
Chloride channel
FXR
LDL
Opioid Receptor
TLR
Na+/Ca2+ Exchanger
Amino Acids and Derivatives
Trk receptor
HIF/HIF Prolyl-Hydroxylase
TGF-beta/Smad
Acyltransferase
TAM Receptor
P2X Receptor
Fatty Acid Synthase
FAK
Sigma receptor
Imidazoline Receptor
NOS
Epoxide Hydrolase
GPCR
cAMP
Ephrin Receptor
Bcl-2 Family
HIF
DPP-4
Chk
MAPK
RSV
Ras
Myosin
HSP
Neprilysin
PGE Synthase
Protease-activated Receptor
Na-K-Cl cotransporter
Lipid
transporter
S6 Kinase
ABC Transporter
Sirtuin
MTP
DNA Alkylator/Crosslinker
Leukotriene Receptor
NADPH-oxidase
p53
Arginase
HCN Channel
PAI-1
ALK
Reverse Transcriptase
MDM-2/p53
Platelet aggregation
Immunology/Inflammation related
Syk
Thyroid hormone receptor(THR)
Reductase
Estrogen Receptor/ERR
CSF-1R
Endothelin Receptor
Histone Methyltransferase
RIP kinase
UGT
Androgen Receptor
Vitamin
Transferase
IFNAR
Necroptosis
Annexin A
PDK
SGK
DNA Methyltransferase
AhR
Factor VIIa
LTR
Histone Demethylase
Monoamine Transporter
FAAH
CCR
glycosidase
DNA
Casein Kinase
CFTR
Monocarboxylate transporter
Phosphatase
Amylase
Prolyl Endopeptidase (PREP)
Xanthine Oxidase
OXPHOS
FKBP
MLK
Rho
Gap Junction Protein
IRAK
ROR
Gamma-secretase
GPCR19
DHFR
Glucosidase
DNA Alkylation
Estrogen/progestogen Receptor
LPL Receptor
Antifolate
PYK2
Adenylate cyclase
Antifection
Thrombopoietin Receptor
Aminopeptidase
ASK
PGC-1α
YAP
OCT
IDO
GRK
Arp2/3 Complex
ACK1
SGLT
Antiviral
N-Acetylglucosaminyltransferase
HBV
VDAC
IAP
Photosystem (PS)
Adiponectin Receptor
Anion Exchanger
ATP Citrate Lyase
Kras
CRISPR/Cas9
HER
HCV Protease
DprE1
Cysteine Protease
Aryl Hydrocarbon Receptor
IRE1
DNA gyrase
CXCR
STING
LRRK2
Retinoid Receptor
RXFP receptor
Cannabinoid Receptor
PKM
Progesterone Receptor
CaSR
Isocitrate Dehydrogenase (IDH)
Vasopressin Receptor
AIM2
GST
Aromatase
ROS Kinase
Lipase
Cell Cycle Arrest
Glucokinase
PAFR
OAT
PLK
Tight Junction Protein
S1P Receptor
NPC1L1
DNA-PK
TOPK
FLAP
Hedgehog/Smoothened
Decarboxylase
MIF
Neurotensin Receptor
GlyT
Indoleamine 2,3-Dioxygenase (IDO)
BCRP
Cuproptosis
Discoidin Domain Receptor (DDR)
p97
ADC Cytotoxin
Sodium-dependent phosphate transporter
BTK

Keywords

Target-based screeningSmall molecule compoundsPhenotypic screeningHypertensionHigh-throughput screeningHeart failureCoronary heart diseaseCompound libraryCardiovascular screening libraryCardiovascular researchCardiovascular lead compoundsCardiovascular drug discoveryCardiovascular disorderCardiovascular diseaseAtherosclerosisAntiCardiovascular Disease Compound LibraryAnti Cardiovascular Disease Compound Library
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