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TargetMol | Compound Library

Anti-Cardiovascular Disease Compound Library

Catalog No. L5400

Cardiovascular disease generally refers to all types of diseases that affect the heart or blood vessels, including coronary heart disease (clogged arteries), which can cause heart attacks, stroke, congenital heart defects and peripheral artery disease, and is the leading cause of death for men and women in the U.S. Different types of cardiovascular diseases have different mechanisms of pathogenesis. Antioxidants, lipid-lowering agents, anti-ischemic drugs, and platelet aggregation inhibitors all can reduce cardiovascular disease risk. Some natural products can inhibit the gene expression of cell adhesion molecules, cytokine, and chemokine, inhibit the function of platelet, enhance the release of nitric oxide by endothelial cells, and inhibit the contraction of smooth muscle.

A unique collection of 1793 cardiovascular diseases related compounds by TargetMol can be used for cardiovascular diseases related research and high throughput and high content screening for new drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L5400

Anti-Cardiovascular Disease Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1793 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved by FDA, EMA, or NMPA;
  • Covers various major targets including membrane transporter, ion channel, etc.; Effect tool for research in cardiovascular disease.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Supporting Files | TargetMol Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (60.2 MB)

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Adrenergic Receptor
Apoptosis
Calcium Channel
PDE
Autophagy
VEGFR
Endogenous Metabolite
COX
Sodium Channel
Potassium Channel
NF-κB
Antibacterial
5-HT Receptor
AChR
TNF
ROS
RAAS
PDGFR
Dopamine Receptor
Parasite
Angiotensin-converting Enzyme (ACE)
FGFR
IL Receptor
p38 MAPK
c-Kit
Histone Acetyltransferase
Interleukin
PARP
Histamine Receptor
FLT
PPAR
ERK
Akt
Reactive Oxygen Species
Drug Metabolite
CDK
NO Synthase
Cytochromes P450
HMG-CoA Reductase
EGFR
PKC
DNA/RNA Synthesis
Factor Xa
JAK
Epigenetic Reader Domain
Antifungal
BACE
Adenosine Receptor
PI3K
Prostaglandin Receptor
Antioxidant
Antibiotic
Caspase
Influenza Virus
Carbonic Anhydrase
IGF-1R
Mitophagy
ATPase
Src
Ferroptosis
c-Met/HGFR
c-RET
HIV Protease
JNK
Beta-Secretase
Thrombin
PKA
SARS-CoV
Phospholipase
Norepinephrine
Nrf2
TRP/TRPV Channel
P2Y Receptor
Glucocorticoid Receptor
STAT
NOD-like Receptor (NLR)
GSK-3
P-gp
CaMK
Beta Amyloid
Wnt/beta-catenin
Cholinesterase (ChE)
Proteasome
Integrin
Mitochondrial Metabolism
iGluR
HDAC
Lipoxygenase
GABA Receptor
AMPK
Guanylate cyclase
Raf
Anti-infection
Virus Protease
MRP
Bcr-Abl
c-Fms
MEK
Monoamine Oxidase
Serotonin Transporter
LDLR
Aurora Kinase
Proton pump
Acetyl-CoA Carboxylase
Tyrosinase
Serine Protease
NMDAR
Dehydrogenase
ROCK
Tyrosine Kinases
Hydroxylase
Tie-2
IκB/IKK
Microtubule Associated
Glutathione Peroxidase
Topoisomerase
MMP
NADPH
MAO
Bcl-2 Family
NOD
TGF-beta/Smad
Acyltransferase
TAM Receptor
P2X Receptor
Fatty Acid Synthase
FAK
Chloride channel
Serine/threonin kinase
FXR
LDL
Opioid Receptor
TLR
Amino Acids and Derivatives
Trk receptor
HIF/HIF Prolyl-Hydroxylase
CETP
PERK
Nucleoside Antimetabolite/Analog
HSV
GluR
mTOR
Na+/Ca2+ Exchanger
Liver X Receptor
Myosin
HSP
Neprilysin
PGE Synthase
Protease-activated Receptor
NOS
Epoxide Hydrolase
p53
DPP-4
Chk
MAPK
RSV
Ras
Sirtuin
Sigma receptor
Imidazoline Receptor
GPCR
cAMP
Ephrin Receptor
HIF
Thyroid hormone receptor(THR)
Reductase
Estrogen Receptor/ERR
CSF-1R
Endothelin Receptor
Histone Methyltransferase
RIP kinase
UGT
Androgen Receptor
DNA Alkylator/Crosslinker
Leukotriene Receptor
NADPH-oxidase
Immunology/Inflammation related
Syk
Na-K-Cl cotransporter
Lipid
transporter
PDK
S6 Kinase
Arginase
HCN Channel
PAI-1
ALK
Reverse Transcriptase
MDM-2/p53
Platelet aggregation
Vitamin
MTP
DHFR
Glucosidase
DNA Alkylation
Adenylyl Cyclase
Estrogen/progestogen Receptor
LPL Receptor
Antifolate
PYK2
Antifection
Thrombopoietin Receptor
Aminopeptidase
ASK
Monocarboxylate transporter
Phosphatase
Amylase
Prolyl Endopeptidase (PREP)
Xanthine Oxidase
OXPHOS
FKBP
MLK
ROR
Gamma-secretase
GPCR19
Transferase
IFNAR
Necroptosis
Annexin A
SGK
DNA Methyltransferase
AhR
Factor VIIa
LTR
Histone Demethylase
ABC Transporter
Monoamine Transporter
FAAH
CCR
glycosidase
DNA
Casein Kinase
CFTR
Rho
Gap Junction Protein
IRAK
NPC1L1
DNA-PK
TOPK
FLAP
Hedgehog/Smoothened
Decarboxylase
MIF
Neurotensin Receptor
GlyT
Indoleamine 2,3-Dioxygenase (IDO)
BCRP
Cuproptosis
Discoidin Domain Receptor (DDR)
p97
HCV Protease
DprE1
Cysteine Protease
Aryl Hydrocarbon Receptor
IRE1
DNA gyrase
CXCR
STING
LRRK2
Retinoid Receptor
RXFP receptor
Cannabinoid Receptor
PKM
Lipase
Cell Cycle Arrest
Glucokinase
PAFR
OAT
PLK
Tight Junction Protein
S1P Receptor
YAP
OCT
IDO
GRK
Arp2/3 Complex
ACK1
SGLT
Antiviral
N-Acetylglucosaminyltransferase
HBV
VDAC
IAP
Photosystem (PS)
Adiponectin Receptor
Anion Exchanger
ATP Citrate Lyase
Kras
CRISPR/Cas9
HER
Progesterone Receptor
CaSR
Isocitrate Dehydrogenase (IDH)
Vasopressin Receptor
AIM2
GST
Aromatase
ROS Kinase
Sodium-dependent phosphate transporter
ADC Cytotoxin
PGC-1α
BTK

Keywords

Target-based screeningSmall molecule compoundsPhenotypic screeningHypertensionHigh-throughput screeningHeart failureCoronary heart diseaseCompound libraryCardiovascular screening libraryCardiovascular researchCardiovascular lead compoundsCardiovascular drug discoveryCardiovascular disorderCardiovascular diseaseAtherosclerosisAntiCardiovascular Disease Compound LibraryAnti Cardiovascular Disease Compound Library
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