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TargetMol | Compound Library

Anti-Cardiovascular Disease Compound Library

Catalog No. L5400

Cardiovascular disease generally refers to all types of diseases that affect the heart or blood vessels, including coronary heart disease (clogged arteries), which can cause heart attacks, stroke, congenital heart defects and peripheral artery disease, and is the leading cause of death for men and women in the U.S. Different types of cardiovascular diseases have different mechanisms of pathogenesis. Antioxidants, lipid-lowering agents, anti-ischemic drugs, and platelet aggregation inhibitors all can reduce cardiovascular disease risk. Some natural products can inhibit the gene expression of cell adhesion molecules, cytokine, and chemokine, inhibit the function of platelet, enhance the release of nitric oxide by endothelial cells, and inhibit the contraction of smooth muscle.

A unique collection of 1793 cardiovascular diseases related compounds by TargetMol can be used for cardiovascular diseases related research and high throughput and high content screening for new drugs.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L5400

Anti-Cardiovascular Disease Compound Library

size

  • 1 mg
  • 10 µL x 10 mM (in DMSO)
  • 20 µL x 10 mM (in DMSO)
  • 30 µL x 10 mM (in DMSO)
  • 50 µL x 10 mM (in DMSO)
  • 100 µL x 10 mM (in DMSO)
  • 250 µL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1793 cardiovascular diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Bioactivity and safety confirmed by pre-clinical research and clinical trials and most of them are approved by FDA, EMA, or NMPA;
  • Covers various major targets including membrane transporter, ion channel, etc.; Effect tool for research in cardiovascular disease.
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

Supporting Files | TargetMol Supporting Files

Library Handling Instructions (635 KB) Targetmol Library Catalog (60.2 MB)

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

Adrenergic Receptor
Apoptosis
Calcium Channel
PDE
Autophagy
VEGFR
Endogenous Metabolite
COX
Sodium Channel
Potassium Channel
NF-κB
Antibacterial
5-HT Receptor
TNF
AChR
ROS
Dopamine Receptor
RAAS
PDGFR
Parasite
Angiotensin-converting Enzyme (ACE)
FGFR
c-Kit
IL Receptor
p38 MAPK
Histamine Receptor
Interleukin
PARP
Histone Acetyltransferase
Reactive Oxygen Species
FLT
PPAR
Drug Metabolite
ERK
Akt
CDK
NO Synthase
Cytochromes P450
HMG-CoA Reductase
EGFR
PKC
Adenosine Receptor
Factor Xa
DNA/RNA Synthesis
JAK
Epigenetic Reader Domain
BACE
Influenza Virus
PI3K
Prostaglandin Receptor
Antifungal
Antibiotic
Antioxidant
Carbonic Anhydrase
IGF-1R
Ferroptosis
c-Met/HGFR
Mitophagy
Src
Caspase
c-RET
Norepinephrine
HIV Protease
JNK
Beta-Secretase
ATPase
TRP/TRPV Channel
Thrombin
Nrf2
PKA
Phospholipase
Glucocorticoid Receptor
STAT
NOD-like Receptor (NLR)
P2Y Receptor
CaMK
Beta Amyloid
P-gp
GABA Receptor
GSK-3
SARS-CoV
Wnt/beta-catenin
iGluR
Cholinesterase (ChE)
HDAC
Mitochondrial Metabolism
Lipoxygenase
Integrin
AMPK
Raf
MRP
Guanylate cyclase
Virus Protease
MEK
Anti-infection
Monoamine Oxidase
Bcr-Abl
NMDAR
c-Fms
Dehydrogenase
ROCK
Aurora Kinase
Tyrosinase
Serine Protease
Serotonin Transporter
LDLR
Tyrosine Kinases
Hydroxylase
NADPH
Microtubule Associated
Proton pump
Glutathione Peroxidase
Serine/threonin kinase
Topoisomerase
Acetyl-CoA Carboxylase
MMP
Liver X Receptor
MAO
NOD
Tie-2
IκB/IKK
CETP
P2X Receptor
Fatty Acid Synthase
FAK
Chloride channel
FXR
LDL
Opioid Receptor
TLR
Amino Acids and Derivatives
Trk receptor
HIF/HIF Prolyl-Hydroxylase
Na+/Ca2+ Exchanger
TGF-beta/Smad
Acyltransferase
TAM Receptor
PERK
Nucleoside Antimetabolite/Analog
HSV
GluR
mTOR
PGE Synthase
Protease-activated Receptor
NOS
Epoxide Hydrolase
DPP-4
Chk
MAPK
RSV
Ras
GPCR
cAMP
Ephrin Receptor
Bcl-2 Family
HIF
Proteasome
Myosin
HSP
Neprilysin
Sigma receptor
Imidazoline Receptor
Na-K-Cl cotransporter
Lipid
transporter
S6 Kinase
Histone Methyltransferase
RIP kinase
UGT
Androgen Receptor
MTP
DNA Alkylator/Crosslinker
Leukotriene Receptor
NADPH-oxidase
p53
Immunology/Inflammation related
Syk
Arginase
HCN Channel
PAI-1
ALK
Reverse Transcriptase
MDM-2/p53
Platelet aggregation
Thyroid hormone receptor(THR)
Reductase
Estrogen Receptor/ERR
CSF-1R
Endothelin Receptor
ABC Transporter
Sirtuin
Vitamin
Transferase
IFNAR
Necroptosis
Annexin A
PDK
SGK
DNA Methyltransferase
AhR
Estrogen/progestogen Receptor
LPL Receptor
Antifolate
PYK2
Adenylate cyclase
Antifection
Thrombopoietin Receptor
Aminopeptidase
ASK
Monocarboxylate transporter
Phosphatase
Amylase
Prolyl Endopeptidase (PREP)
Xanthine Oxidase
OXPHOS
FKBP
MLK
ROR
PAFR
Gamma-secretase
GPCR19
Rho
Gap Junction Protein
IRAK
DHFR
Glucosidase
DNA Alkylation
Factor VIIa
LTR
Histone Demethylase
Monoamine Transporter
FAAH
CCR
glycosidase
DNA
Casein Kinase
CFTR
PGC-1α
YAP
OCT
IDO
GRK
Arp2/3 Complex
ACK1
SGLT
Antiviral
MIF
Neurotensin Receptor
GlyT
Indoleamine 2,3-Dioxygenase (IDO)
BCRP
Cuproptosis
Discoidin Domain Receptor (DDR)
p97
HCV Protease
DprE1
Cysteine Protease
Aryl Hydrocarbon Receptor
IRE1
DNA gyrase
CXCR
STING
LRRK2
Retinoid Receptor
RXFP receptor
Cannabinoid Receptor
PKM
Lipase
Cell Cycle Arrest
Glucokinase
PANoptosis
OAT
Protease
PLK
Tight Junction Protein
S1P Receptor
Progesterone Receptor
CaSR
BTK
Isocitrate Dehydrogenase (IDH)
Vasopressin Receptor
AIM2
GST
Aromatase
Dipeptidyl Peptidase
ROS Kinase
NPC1L1
DNA-PK
TOPK
FLAP
Hedgehog/Smoothened
Decarboxylase
N-Acetylglucosaminyltransferase
HBV
VDAC
IAP
Photosystem (PS)
Adiponectin Receptor
Anion Exchanger
ATP Citrate Lyase
Kras
CRISPR/Cas9
HER
ADC Cytotoxin
Sodium-dependent phosphate transporter

Keywords

Target-based screeningSmall molecule compoundsPhenotypic screeningHypertensionHigh-throughput screeningHeart failureCoronary heart diseaseCompound libraryCardiovascular screening libraryCardiovascular researchCardiovascular lead compoundsCardiovascular drug discoveryCardiovascular disorderCardiovascular diseaseAtherosclerosisAntiCardiovascular Disease Compound LibraryAnti Cardiovascular Disease Compound Library
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