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Kanshone A

Name: Kanshone A
Brand: TargetMol
SKU: TN4376
Rating: 4.5 (1 reviews)

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Catalog No. TN4376Cas No. 115356-18-8

Kanshone A, a sesquiterpenoid naturally derived from Nardostachys chinensis, is cytotoxic and inhibits the proliferation of P-388 leukemia cells.

Kanshone A

😃Good

Catalog No. TN4376Cas No. 115356-18-8

Kanshone A, a sesquiterpenoid naturally derived from Nardostachys chinensis, is cytotoxic and inhibits the proliferation of P-388 leukemia cells.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
5 mg	$1,869	Inquiry	Inquiry
1 mL x 10 mM (in DMSO)	$2,058	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description

Kanshone A, a sesquiterpenoid naturally derived from Nardostachys chinensis, is cytotoxic and inhibits the proliferation of P-388 leukemia cells.

In vitro

Methods: The active ingredients of Nardostachys grandiflora were studied, and the compounds were separated and purified by chromatography. Their structures were identified by spectral analysis and comparison with public data.
Results: A total of 9 compounds were obtained, which were identified as acacetin, ursolic acid, octacosanol, Kanshone A, gansostachysonediol, gansostachysone, aristoyl-9β-ol, oleanolic acid and β-sitosterol. [1]

Chemical Properties

Molecular Weight	234.33
Formula	C₁₅H₂₂O₂
Cas No.	115356-18-8
Smiles	C[C@@H]1CCC=C2C(=O)C=C[C@@H](C(C)(C)O)[C@@]12C
Relative Density.	1.05 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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Keywords

Kanshone A