PD-1 Protein, Human, Recombinant (CHO, hFc)

Name: PD-1 Protein, Human, Recombinant (CHO, hFc)
Brand: TargetMol
SKU: TMPS-00113
Rating: 4.5 (1 reviews)

(Synonyms: Programmed cell death 1, PDCD1, PD-1, CD279) Copy Product Info

Synonyms: Programmed cell death 1, PDCD1, PD-1, CD279

Catalog No. TMPS-00113 Copy Product Info

PD-1 Protein, Human, Recombinant (CHO, hFc) is expressed in CHO Cells. The accession number is Q15116.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$55	7-10 days	7-10 days
10 µg	$86	-	In Stock
20 µg	$138	7-10 days	7-10 days
50 µg	$272	-	In Stock
100 µg	$458	7-10 days	7-10 days
200 µg	$777	7-10 days	7-10 days
500 µg	$1,570	7-10 days	7-10 days
1 mg	$2,680	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 98% as analyzed by SDS-PAGE

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	1. Immobilized PD-L1, hFc, Human at 1.0 μg/ml (100 μl/well) can bind biotinylated PD-1, hFc, Human. 2. Immobilized PD-L1, His, Human at 2.0 μg/ml (100 µl/well) can bind PD-1, hFc, Human.
Description	PD-1 Protein, Human, Recombinant (CHO, hFc) is expressed in CHO Cells. The accession number is Q15116.
Species	Human
Expression System	CHO Cells
Tag	hFc
Accession Number	Q15116
Construction	Leu25-Gln167
Protein Purity	> 98% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Programmed cell death 1, PDCD1, PD-1, CD279
Research Background	Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279) or PDCD1, is a protein that in humans is encoded by the PDCD1 gene. PD-1 is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells and pro-B cells.PD-1 binds two ligands, PD-L1 and PD-L2. PD-1 and its ligands play an important role in down regulating the immune system by preventing the activation of T-cells, which in turn reduces autoimmunity and promotes self-tolerance. The inhibitory effect of PD-1 is accomplished through a dual mechanism of promoting apoptosis (programmed cell death) in antigen specific T-cells in lymph nodes while simultaneously reducing apoptosis in regulatory T cells (suppressor T cells)

Chemical Properties

Molecular Weight

60~65 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.