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Anti-CD64 Antibody (9F168)

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Catalog No. TMAY-03086
Alias Fc γ RI, Fc receptor, IgG, high affinity I, Fc gamma RI, CD64

Anti-CD64 Antibody (9F168) is a Rabbit antibody targeting CD64. Anti-CD64 Antibody (9F168) can be used in ELISA,IHC-P.

Anti-CD64 Antibody (9F168)

Anti-CD64 Antibody (9F168)

😃Good
Catalog No. TMAY-03086Alias Fc γ RI, Fc receptor, IgG, high affinity I, Fc gamma RI, CD64
Anti-CD64 Antibody (9F168) is a Rabbit antibody targeting CD64. Anti-CD64 Antibody (9F168) can be used in ELISA,IHC-P.
Pack SizePriceAvailabilityQuantity
20 μL$92 7-10 days
100 μL$294 7-10 days
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Product Introduction

Bioactivity
Description
Anti-CD64 Antibody (9F168) is a Rabbit antibody targeting CD64. Anti-CD64 Antibody (9F168) can be used in ELISA,IHC-P.
AliasFc γ RI, Fc receptor, IgG, high affinity I, Fc gamma RI, CD64
Ig Type
Monoclonal Rabbit IgG
Clone
9F168
Reactivity
Mouse
Verified Activity
1. Immunochemical staining of mouse FCGR1 in mouse spleen with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). The left panel: tissue incubated with primary antibody; The right panel: tissue incubated with the mixture of primary antibody and antigen (recombinant protein).

2. Immunochemical staining of mouse FCGR1 in mouse liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to Kupffer cell.

3. Immunochemical staining of mouse FCGR1 in mouse brain with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to microglia.
Application
ELISA,IHC-P
Recommended Dose
ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse FCGR1 extracellular domain (rM FCGR1; TMPY-01205; NP_034316.1; Met 1-Pro 297).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundHigh affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membraneglycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of asignal peptidethat allows its transport to the surface of a cell, threeextracellularimmunoglobulin domainsof the C2-type that it uses to bind antibody, a hydrophobictransmembrane domain, and a short cytoplasmic tail. CD64 isconstitutivelyfound on only macrophages and monocytes, but treatment of polymorphonuclear leukocyteswith cytokines likeIFNγandG-CSFcan induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Mouse FCGR1 protein (TMPY-01205)
Antigen Species
Mouse
Biology Area
Fc Receptors
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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