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L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside

Name: L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside
Brand: TargetMol
SKU: TN1447
Price: 73 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: OJV-II, Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside) Copy Product Info

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Synonyms: OJV-II, Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside

Catalog No. TN1447 Copy Product Info

Purity: 99.28%

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L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside alleviates myocardial ischemia-reperfusion injury in rats and hypoxic/reoxygenated injured myocardial cells via regulating the PI3K/AKT/mTOR signaling pathway. L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside is therefore studied in cardiovascular ischemia–reperfusion experimental models to investigate PI3K/AKT/mTOR pathway modulation, cellular stress response regulation, and cardiomyocyte injury-associated signaling dynamics in hypoxia/reoxygenation systems.

Cas No. 88700-35-0

Pack Size	Price	USA Stock	Global Stock
1 mg	$73	-	In Stock
5 mg	$185	-	In Stock
10 mg	$273	-	In Stock
25 mg	$463	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:99.28%

Appearance:Solid

Color:White

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Product Introduction

Bioactivity

Description	L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside alleviates myocardial ischemia-reperfusion injury in rats and hypoxic/reoxygenated injured myocardial cells via regulating the PI3K/AKT/mTOR signaling pathway. L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside is therefore studied in cardiovascular ischemia–reperfusion experimental models to investigate PI3K/AKT/mTOR pathway modulation, cellular stress response regulation, and cardiomyocyte injury-associated signaling dynamics in hypoxia/reoxygenation systems.
In vivo	Method: Cardiac histopathological analysis using HE staining and TTC staining was performed in IR rats with L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside (LBAG) or Ver pretreatment. Result: IR group showed irregular myocardial cell arrangement, partial lysis in the infarct border zone, and cardiac muscle fiber breakage. LBAG or Ver pretreatment partially reversed these histological changes. TTC staining showed increased myocardial infarction size in MIRI rats, while LBAG or Ver pretreatment significantly reduced infarct areas compared with the IR group.
Synonyms	OJV-II, Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside

Chemical Properties

Molecular Weight	448.50
Formula	C₂₁H₃₆O₁₀
Cas No.	88700-35-0
Smiles	O([C@H]1[C@]2(C)C(C)(C)[C@](C1)(CC2)[H])[C@@H]3O[C@H](CO[C@H]4[C@H](O)[C@](CO)(O)CO4)[C@@H](O)[C@H](O)[C@H]3O
Relative Density.	1.43 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

LBorneol 7O[βDapiofuranosyl(1→6)]βDglucopyranosideL Borneol 7 O [β D apiofuranosyl (1→6)] β D glucopyranosideFT-0775891FT0775891FT 0775891

Related Tags: L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside chemical structure | L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside in vivo | L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside formula | L-Borneol 7-O-[β-D-apiofuranosyl-(1→6)]-β-D-glucopyranoside molecular weight