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Anti-NALP6 Polyclonal Antibody
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Catalog No. TMAB-01200
Alias PYRIN containing APAF1 like protein 5, PYPAF5, PAN3, Nucleotide binding oligomerization domain, leucine rich repeat and pyrin domain containing 6, Nlrp6, NLR family, pyrin domain containing 6, NALP6, NACHT, LRR and PYD domains-containing protein 6, NACHT, LRR and PYD containing protein 6, NACHT, leucine rich repeat and PYD containing 6, CLR11.4
Anti-NALP6 Polyclonal Antibody is a Rabbit antibody targeting NALP6. Anti-NALP6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-NALP6 Polyclonal Antibody
Anti-NALP6 Polyclonal Antibody
😃Good
Catalog No. TMAB-01200Alias PYRIN containing APAF1 like protein 5, PYPAF5, PAN3, Nucleotide binding oligomerization domain, leucine rich repeat and pyrin domain containing 6, Nlrp6, NLR family, pyrin domain containing 6, NALP6, NACHT, LRR and PYD domains-containing protein 6, NACHT, LRR and PYD containing protein 6, NACHT, leucine rich repeat and PYD containing 6, CLR11.4
Anti-NALP6 Polyclonal Antibody is a Rabbit antibody targeting NALP6. Anti-NALP6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $528 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-NALP6 Polyclonal Antibody is a Rabbit antibody targeting NALP6. Anti-NALP6 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Alias | PYRIN containing APAF1 like protein 5, PYPAF5, PAN3, Nucleotide binding oligomerization domain, leucine rich repeat and pyrin domain containing 6, Nlrp6, NLR family, pyrin domain containing 6, NALP6, NACHT, LRR and PYD domains-containing protein 6, NACHT, LRR and PYD containing protein 6, NACHT, leucine rich repeat and PYD containing 6, CLR11.4 |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human) |
| Verified Activity | 1. Tissue/cell: rat kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-NALP6 Polyclonal Antibody, Unconjugated (TMAB-01200) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. 2. Tissue/cell: mouse intestine tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-NALP6 Polyclonal Antibody, Unconjugated (TMAB-01200) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cytoplasm. Cell membrane. Nucleus membrane. Isoform 2: Cytoplasm. Cell membrane. Note=Predominantly expressed in the cell membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM, Mar 2008] |
| Immunogen | KLH conjugated synthetic peptide: human NALP6 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Caspases,Macrophage / Inflamm.,NFkB Pathway |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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