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Synonyms: MMP13, Matrix metalloproteinase-13 (MMP-13), Collagenase 3
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-MMP-13 Polyclonal Antibody is a Rabbit antibody targeting MMP-13. Anti-MMP-13 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | MMP13, Matrix metalloproteinase-13 (MMP-13), Collagenase 3 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix (Probable). |
| Tissue Specificity | Seems to be specific to breast carcinomas. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human MMP13 |
| Antigen Species | Human |
| Gene Name | MMP13 |
| Gene ID | |
| Protein Name | Collagenase 3 |
| Uniprot ID | |
| Biology Area | MMPs,MMPs,MMPs,MMP,MMPs,Tumor biomarkers ELISA kits,MMP |
| Function | Degrades collagen type I. Does not act on gelatin or casein. Could have a role in tumoral process. |
| Molecular Weight | Theoretical: 52 kDa. Actual: 60 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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