ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc)

Name: ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc)
Brand: TargetMol
SKU: TMPJ-00324
Rating: 4.5 (1 reviews)

(Synonyms: Intercellular adhesion molecule 1, ICAM-1, ICAM1, CD54) Copy Product Info

Synonyms: Intercellular adhesion molecule 1, ICAM-1, ICAM1, CD54

Catalog No. TMPJ-00324 Copy Product Info

Intercellular adhesion molecule 1 (ICAM1) is known as CD54. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.

ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc)

Pack Size	Price	USA Stock	Global Stock
5 µg	$51	7-10 days	7-10 days
10 µg	$80	7-10 days	7-10 days
20 µg	$128	7-10 days	7-10 days
50 µg	$247	7-10 days	7-10 days
100 µg	$458	7-10 days	7-10 days
200 µg	$866	7-10 days	7-10 days
500 µg	$2,010	7-10 days	7-10 days
1 mg	$3,020	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Intercellular adhesion molecule 1 (ICAM1) is known as CD54. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.
Species	Rhesus
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q5NKV6
Amino Acid	Gln28-Glu480
Construction	Gln28-Glu480
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Intercellular adhesion molecule 1, ICAM-1, ICAM1, CD54
Research Background	Intercellular adhesion molecule 1 (ICAM1) is known as CD54. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. The endothelial expression of ICAM-1 is increased in atherosclerotic and transplant-associated atherosclerotic tissue and animal models of atherosclerosis. Additionally, ICAM-1 has been implicated in the progression of autoimmune diseases. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.

Chemical Properties

Molecular Weight

100-130 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

ICAM 1CD-54CD 54

Related Tags: ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc) chemical structure | ICAM-1/CD54 Protein, Rhesus macaque, Recombinant (hFc) molecular weight