HSP27/HSPB1 Protein, Human, Recombinant (His)

Name: HSP27/HSPB1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPK-00693
Rating: 4.5 (1 reviews)

(Synonyms: SRP27, HSPB1, HSP28, Hsp27, HSP 27, HMN2B, CMT2F) Copy Product Info

Synonyms: SRP27, HSPB1, HSP28, Hsp27, HSP 27, HMN2B, CMT2F

Catalog No. TMPK-00693 Copy Product Info

Heat shock protein beta-1 (HSPB1, also known as HSP27) is a small heat shock protein involved in many cellular processes and reportedly protects cells against oxidative stress. This protein is expressed only in insulin-dependent tissues (heart, skeletal muscle, and fat tissue), and expression of HspB7 is regulated by many different factors. HspB7 has an unusual N-terminal sequence, a conservative α-crystallin domain, and very short C-terminal domain lacking conservative IPV tripeptide involved in a small heat shock proteins oligomer formation.

HSP27/HSPB1 Protein, Human, Recombinant (His)

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Pack Size	Price	USA Stock	Global Stock
5 µg	$56	7-10 days	7-10 days
10 µg	$88	7-10 days	7-10 days
20 µg	$143	7-10 days	7-10 days
50 µg	$278	7-10 days	7-10 days
100 µg	$465	7-10 days	7-10 days
200 µg	$839	7-10 days	7-10 days
500 µg	$1,850	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Heat shock protein beta-1 (HSPB1, also known as HSP27) is a small heat shock protein involved in many cellular processes and reportedly protects cells against oxidative stress. This protein is expressed only in insulin-dependent tissues (heart, skeletal muscle, and fat tissue), and expression of HspB7 is regulated by many different factors. HspB7 has an unusual N-terminal sequence, a conservative α-crystallin domain, and very short C-terminal domain lacking conservative IPV tripeptide involved in a small heat shock proteins oligomer formation.
Species	Human
Expression System	E. coli
Tag	C-His
Accession Number	P04792
Construction	Met1-Lys205
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 2 mM DTT (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	SRP27, HSPB1, HSP28, Hsp27, HSP 27, HMN2B, CMT2F
Research Background	Heat shock protein beta-1 (HSPB1, also known as HSP27) is a small heat shock protein involved in many cellular processes and reportedly protects cells against oxidative stress. This protein is expressed only in insulin-dependent tissues (heart, skeletal muscle, and fat tissue), and expression of HspB7 is regulated by many different factors. HspB7 has an unusual N-terminal sequence, a conservative α-crystallin domain, and very short C-terminal domain lacking conservative IPV tripeptide involved in a small heat shock proteins oligomer formation.

Chemical Properties

Molecular Weight

23.74 kDa (predicted). The protein migrates to 25-30 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.