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CD16 Protein, Cynomolgus, Recombinant (His)
(Synonyms: IMD20, IgG Fc receptor III, IGFR3, Fc-γ RIII, FCRIIIA, FcRIII, FCR-10, FcgRIII, FCGR3, Fc-gamma RIII, FCG3, Fc γ RIIB, CD16A, CD16) Copy Product InfoSynonyms: IMD20, IgG Fc receptor III, IGFR3, Fc-γ RIII, FCRIIIA, FcRIII, FCR-10, FcgRIII, FCGR3, Fc-gamma RIII, FCG3, Fc γ RIIB, CD16A, CD16
Catalog No. TMPK-01115 Copy Product Info
Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIIA, and FcRn receptors has been determined.A common set of IgG1 residues is involved in binding to all Fc gamma R; Fc gamma RII and Fc gamma RIII also utilize residues outside this common set.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $46 | 7-10 days | 7-10 days | |
| 10 μg | $72 | 7-10 days | 7-10 days | |
| 20 μg | $115 | 7-10 days | 7-10 days | |
| 50 μg | $222 | 7-10 days | 7-10 days | |
| 100 μg | $371 | 7-10 days | 7-10 days | |
| 200 μg | $673 | 7-10 days | 7-10 days | |
| 500 μg | $1,490 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for human Fc gamma RI, Fc gamma RIIA, Fc gamma RIIB, Fc gamma RIIIA, and FcRn receptors has been determined.A common set of IgG1 residues is involved in binding to all Fc gamma R; Fc gamma RII and Fc gamma RIII also utilize residues outside this common set. |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | Q8SPW2-1 |
| Construction | Gly17-Gln208 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | IMD20, IgG Fc receptor III, IGFR3, Fc-γ RIII, FCRIIIA, FcRIII, FCR-10, FcgRIII, FCGR3, Fc-gamma RIII, FCG3, Fc γ RIIB, CD16A, CD16 |
| Research Background |
| Molecular Weight | 23.1 kDa (predicted). Due to glycosylation, the protein migrates to 45-55 kDa based on Tris-Bis PAGE result. |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: CD16 Protein, Cynomolgus, Recombinant (His) chemical structure | CD16 Protein, Cynomolgus, Recombinant (His) molecular weight
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