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Anti-ST2/IL-1 RL1 Antibody (8P794) is a Rabbit antibody targeting ST2/IL-1 RL1. Anti-ST2/IL-1 RL1 Antibody (8P794) can be used in ELISA.
Description | Anti-ST2/IL-1 RL1 Antibody (8P794) is a Rabbit antibody targeting ST2/IL-1 RL1. Anti-ST2/IL-1 RL1 Antibody (8P794) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 8P794 |
Reactivity | Mouse |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL1RL1/IL‑1 R4/ST2 (rM IL1RL1/IL‑1 R4/ST2; TMPY-04096; NP_001020773.1; Met1-Arg332). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines. |
Conjucates | Unconjugated |
Immunogen | Recombinant Mouse IL1RL1/IL‑1 R4/ST2 Protein (TMPY-04096) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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